Pulmonary histiocytosis x from Langerhans’ cells
Abstract
Out of the 75 cases of pulmonary histiocytosis X from Langerhans’ cells under study, the diagnosis found morphological proof in 54. Alongside cytological and hystological tests, we also recurred to electronic microscopic studies, and cell immunotyping with KP-1 (CD-68), MAC-387, and S-100 protein — specific markers of histiocytosis X. This diagnosis is considered proved only when specific markers (Birbeck bodies) and/or the characteristic immunochemical markers of Langerhans’ cells — KP-1 (CD-68) and S-100 protein — are identified in the macrophages of lesion sites.
About the Authors
I. V. Dvorakovskaya
Государственный научный центр пульмонологии М3 РФ
Russian Federation
Russian Federation
B. G. Lisochkin
Государственный научный центр пульмонологии М3 РФ
Russian Federation
Russian Federation
E. M. Dembo
Государственный научный центр пульмонологии М3 РФ
Russian Federation
Russian Federation
E. E. Leenman
Государственный научный центр пульмонологии М3 РФ
Russian Federation
Russian Federation
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Review
For citations:
Dvorakovskaya I.V., Lisochkin B.G., Dembo E.M., Leenman E.E. Pulmonary histiocytosis x from Langerhans’ cells. PULMONOLOGIYA. 1997;(4):68-72. (In Russ.)
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