Survival assessment in adult cystic fibrosis patients
Abstract
Our purpose was to evaluate mortality rates at two years on the basis of lung function in adult cystic fibrosis (CF) patients during 1993-2000.
Forty five adults CF patients were included in our study. The diagnosis was confirmed by the typical clinical findings together with an abnormal sweat test results.
Twelve patients (27%) of all the CF patients died during the study period. Mortality was significant higher (p=0.002) in patients with severe lung disease. Regression analysis confirmed that all the covariants (FEV1, FVC, BMI, sex and age) were reliable predictors of death. Among all the variables, FEV1 was the most significant predictor of mortality.
Standard lung function tests make it possible to assess the survival of adult CF patients.
About the Authors
A. V. Cherniak
НИИ пульмонологам М3 РФ
Russian Federation
Russian Federation
E. L. Amelina
НИИ пульмонологам М3 РФ
Russian Federation
Russian Federation
N. Yu. Kashirskaya
НИИ пульмонологам М3 РФ
Russian Federation
Russian Federation
N. I. Kapranov
НИИ пульмонологам М3 РФ
Russian Federation
Russian Federation
A. L. Cherniaev
НИИ пульмонологам М3 РФ
Russian Federation
Russian Federation
A. G. Chuchalin
НИИ пульмонологам М3 РФ
Russian Federation
Russian Federation
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Review
For citations:
Cherniak A.V., Amelina E.L., Kashirskaya N.Yu., Kapranov N.I., Cherniaev A.L., Chuchalin A.G. Survival assessment in adult cystic fibrosis patients. PULMONOLOGIYA. 2000;(3):62-66. (In Russ.)
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