Study of the ciliary epitelium function in the patients with CF and COPD by lifetime television microscopy
Abstract
25 patients with CF and 20 with others of COPD were examinated. Ciliary beat was measured by a lifetime TV microscopy of bioptates of respiratory mucous. Material was obtained with the help of brush biopsy during fiberoptic bronchoscopy. The image of ciliary beat from a light microscope was recorded on the hard disk of the personal computer. The specially created program estimated ciliary beat frequency (CBF) and amplitude of ciliary beating. CBF into bronchi of the CF patients have made at impact phase – 6.3+0.33 Hz, raising phase – 5.7+0.36 Hz; in the patients with COPD: 6.5+0.32 Hz and 6.2+0.33 Hz accordingly. The precise tendency to a drop of CBF and amplitude of ciliary beating in the patients with CF on a comparison with the patients with COPD and literary datas was marked. Also, the drop of indexes of beating in the patients with Ps.aeruginosae mucoid were marked.
About the Authors
A. G. Tchermensky
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
T. E. Gembitskaya
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
T. S. Sologub
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
A. V. Orlov
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
E. N. Mitkina
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
L. A. Jelenina
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
M. E. Faustova
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
V. V. Shabalin
НИИ пульмонологии СПбГМУ им. акад. И.П.Павлова; Санкт-Петербургская детская городская больница Св.Ольги; Санкт-Петербургский НИИЛОР
Russian Federation
Russian Federation
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Review
For citations:
Tchermensky A.G., Gembitskaya T.E., Sologub T.S., Orlov A.V., Mitkina E.N., Jelenina L.A., Faustova M.E., Shabalin V.V. Study of the ciliary epitelium function in the patients with CF and COPD by lifetime television microscopy. PULMONOLOGIYA. 2001;(3):53-57. (In Russ.)
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