Case of a placental site trophoblastic tumor that manifested a pulmonary hemorrhage
https://doi.org/10.18093/0869-0189-2020-30-1-109-114
Abstract
Placental site trophoblastic tumor (PSTT) is the 3rd most frequently encountered gestational trophoblastic tumor after destructive cystic mole and choriocarcinoma. Currently, according to the literature, just over 600 cases are described in the world. The low incidence of this tumor, the non-specific clinical picture and the lack of changes in the overall clinical analysis pose significant challenges for clinicians in terms of reliable preoperative diagnosis. Clinical observation is made of a 34-year-old patient with PSTT manifested by hemoptysis due to bilateral metastatic lung injury. The diagnosis was verified histologically using immunohistochemical methods of investigation after an open biopsy of pulmonary tissue (lung resection). Then the patient underwent courses of adjuvant chemotherapy, surgical intervention on the opposite lung to remove the remaining tumor deposits Chemotherapy after the second surgery was continued. The patient at the time of writing (within 1 year and 6 months after the first lung operation) is alive, hysterectomy was not performed, clinical and radiological signs of tumor progression are absent.
About the Authors
R. B. Berdnikov
Ural Federal Research Institute of Phthisiology and Pulmonology – A Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia; Ural Federal State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Roman B. Berdnikov, Candidate of Medical Sciences, Senior research assistant at the Laboratory of Diagnostic and Experimental Methods of Research, Head of the Pathological Anatomy Department of the Ural Federal Research Institute of Phthisiology and Pulmonology – A Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia, Associate Professor at the Department of Pathological Anatomy of the Ural Federal State Medical University, Healthcare Ministry of Russia
ul. 22-go Parts’ezda 50, Ekaterinburg, 620039
ul. Repina 3, Ekaterinburg, 620028
tel.: (343) 333-44-46
A. V. Bazhenov
Ural Federal Research Institute of Phthisiology and Pulmonology – A Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Aleksandr V. Bazhenov, Candidate of Medical Sciences, senior research assistant at the Laboratory of Conservative and Surgical Technologies for Treatment of Tuberculosis, Thoracic Surgeon at the Tuberculosis Pulmonary and Surgical Department
ul. 22-go Parts’ezda 50, Ekaterinburg, 620039
tel.: (343) 333-44-38
V. V. Petkau
Ural Federal State Medical University, Healthcare Ministry of Russia; State Autonomous Institution of Healthcare of the Sverdlovsk Region "Sverdlovsk Regional Oncological Dispensary"
Russian Federation
Russian Federation
Vladislav V. Petkau, Candidate of Medical Sciences, oncologist, Head of the polyclinic of the State Autonomous Institution of Healthcare of the Sverdlovsk Region "Sverdlovsk Regional Oncological Dispensary", associate professor of the Department of Oncology and Medical Radiology of the Ural Federal State Medical University, Healthcare Ministry of Russia
ul. Repina 3, Ekaterinburg, 620028
ul. Soboleva 29, Ekaterinburg, 620036
tel.: (343) 356-17-26
A. S. Mal'tseva
Ural Federal Research Institute of Phthisiology and Pulmonology – A Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Anna S. Mal'tseva, radiologist, Radiation Diagnostic Department
ul. 22-go Parts’ezda 50, Ekaterinburg, 620039
tel.: (343) 333-44-33
N. D. Sorokina
Ural Federal State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Natal'ya D. Sorokina, pathologist of the histological department of the Central Research Laboratory
ul. Repina 3, Ekaterinburg, 620028
tel.: (908) 631-87-79
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Review
For citations:
Berdnikov R.B., Bazhenov A.V., Petkau V.V., Mal'tseva A.S., Sorokina N.D. Case of a placental site trophoblastic tumor that manifested a pulmonary hemorrhage. PULMONOLOGIYA. 2020;30(1):109-114. (In Russ.) https://doi.org/10.18093/0869-0189-2020-30-1-109-114
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