Effects of bronchial asthma control on cardiovascular disorders in early school age children
https://doi.org/10.18093/0869-0189-2020-30-1-23-30
Abstract
The course of bronchial asthma (BA) is accompanied by pathological changes in the bronchopulmonary and cardiovascular systems. The severity of heart functional disorders depends on the severity of the BA Course, the level of control and the frequency of application of short-acting β2 -agonists (SAβ2A). The aim of the study was to analyze the impact of BA control on the development of cardiovascular disorders in children of early school age. Methods. Children (n = 95) aged 7–12 years with BA of varying severity and different levels of control were examined. The analysis of indicators of the clinical and functional state of the vegetal nervous system (VNS) and cardiovascular system tone using standard electrocardiography, echocardiography with calculation of the left ventricular myocardial mass index, сardiointervalography was performed. Results. Changes in VNS with signs of its depletion and decrease in adaptive capacity, cardiac rhythm and conduction disorders, connective tissue dysplasia syndrome, hemodynamic disorders and signs of adaptive heart remodeling have been detected. Conclusion. Lack of control over BA and the use of SAβ2A promote cardiovascular disorders.
About the Authors
I. V. Leshchenko
Ural Federal State Medical University, Healthcare Ministry of Russia; «Novaya bol’nitsa» Clinical Association LLC
Russian Federation
Russian Federation
Igor' V. Leshchenko, Doctor of Medicine, Professor, Department of Phthisiology, Pulmonology and Thoracic Surgery, Ural Federal State Medical University, Healthcare Ministry of Russia; Chief Researcher, Ural Federal Research Institute of Phthisiology and Pulmonology, Academic Advisor of «Novaya bol'nitsa» Clinical Association
ul. Repina 3, Ekaterinburg, 620028
ul. Zavodskaya 29, Ekaterinburg, 620109
tel.: (343) 246-44-75
Yu. L. Bazhenova
Ural Federal State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Yuliya L. Bazhenova, Assistant of pediatric Department outpatient Faculty training and retraining
ul. Repina 3, Ekaterinburg, 620028
tel.: (343) 214-86-62
S. A. Tsar'kova
Ural Federal State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Sof'ya A. Tsar'kova, Doctor of Medicine, Professor, Head of the Department of Pediatrics and Department outpatient Faculty training and retraining
ul. Repina 3, Ekaterinburg, 620028
tel.: (343) 214-86-62
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Review
For citations:
Leshchenko I.V., Bazhenova Yu.L., Tsar'kova S.A. Effects of bronchial asthma control on cardiovascular disorders in early school age children. PULMONOLOGIYA. 2020;30(1):23-30. (In Russ.) https://doi.org/10.18093/0869-0189-2020-30-1-23-30
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