December 7, 2021 marks the 150th anniversary of the birth of Dmitry Dmitrievich Pletnev. Being an outstanding therapist, a talented clinician-researcher of internal diseases, a thinker and teacher, a brilliant speaker, one of the founders of cardiology as a separate area in the domestic medicine – D.D.Pletnev had a huge potential that he was not destined to fulfill. His fate was tragic – he was arrested under a fabricated “case” in 1937 and shot in 1941. His name was trampled into the mud and anathematized for many years. And only 47 years later, in 1985, D.D.Pletnev was rehabilitated completely through the efforts of many caring people. He was rehabilitated posthumously “due to the absence of the event of the crime”. The article presents a brief biography and history of the rehabilitation of the honor of D.D.Pletnev*.

Metabolic syndrome is a problem of our time due to its high prevalence (from 20 to 50% in the adult population). 
The aim of the work was to outline the main stages in the study of the totality of hemodynamic and metabolic disorders that was later designated “metabolic syndrome”, in Russia. The article focuses on the development of the ideas of D.D.Pletnev and G.F.Lang from the beginning of the 20th century to the present at the Department of Faculty Therapy in Petrograd Medical Institute for Women, which was later named the First Leningrad Medical Institute and is now named Federal State Budgetary Educational Institution of Higher Education Academician I.P.Pavlov First St. Petersburg State Medical University under the Ministry of Healthcare of Russian Federation. The article discusses current trends in the study of the metabolic syndrome, including data from epidemiological studies on the prevalence of the metabolic syndrome and its individual components in Russia.
Results. The paper presents the results of molecular genetic and instrumental methods for examining patients with abdominal obesity, metabolic syndrome, including those with complications such as atrial fibrillation, coronary heart disease, chronic heart failure with preserved left ventricular fraction. The review presents data on the molecular and other features of subcutaneous and visceral (epicardial) adipose tissue.
Conclusion. The paper outlines priority areas for studying the metabolic syndrome in the future, which will be important for preventing the development and progression of this pathological condition.

The article was first published in the journal “Vrachebnoe delo”. 1935; (2): 103–108. Flashback contains minor editorial changes.

December 7, 2021 marks the 150th anniversary of birth of an outstanding scientist, clinician, publicist and teacher Dmitry D. Pletnev. D.D.Pletnev was convicted unfairly in 1937 and rehabilitated in 1985 by the Supreme Court of the USSR. However, several more decades of the oblivion passed. The understanding of the scientific and practical creativity of this man and his contribution to world medical history – the real rehabilitation – has begun only in the recent years. The sphere of interests and competencies of D.D.Pletnev was extremely extensive. Unfortunately, very few publications of D.D.Pletnev have survived to this day, only one short article “Hypertension (the experience of analyzing its genesis)” was found, published in the journal “Vrachebnoye delo” in 1935

An analysis of the publication of the outstanding Russian therapist and cardiologist Dmitriy D. Pletnev (1871 – 1941) is given in the article. In 1925, he published an article “On the issue of lifetime differential diagnosis of right and left coronary artery thrombosis” in the journal “Russian Clinics” in Russian and German languages. Timely diagnosis of right myocardial infarction determines the prognosis and treatment tactics of this disease, and the case itself has a priority for the Russian science. The authors emphasize the outstanding talent of D.D.Pletnev as a physician and scientist, whose name is associated with the emergence of one of the most brilliant therapeutic schools (A.L.Myasnikov, E.I.Chazov et al.).

The problem of anxiety and depressive disorders (ADD) is one of the most urgent in modern general medical practice. ADD are widespread both in the general population and in the hospital network, especially in outpatient general practice. The article presents the main clinical manifestations of anxiety and depression, emphasizes their polysystemic somatic manifestations and concurrence with cardiovascular diseases. The pathophysiology of the clinical manifestations of anxiety and depression is discussed. A detailed analysis of their diagnosis and main treatment methods is given.

To date, non-invasive assessment of the right parts of the heart remains an urgent problem. 
Relevance. Echocardiography is still one of the principal functional research methods, which allows you to identify pathological changes quickly and objectively in both left and right parts of the heart.
Results. The development and improvement of the technical capabilities of ultrasound scanners leads to new methods for calculating the indicators of the functional state of the heart and a more accurate understanding of the pathological processes occurring in a particular case. 
Conclusion. Echocardiography occupies a leading position in everyday clinical practice because of its safety and the possibility of bedside examination of urgent patients with circulatory failure.

The article provides current information about the clinical manifestations and diagnosis of arrhythmogenic right ventricular cardiomyopathy, highlights the genetic aspects of the disease, and analyzes the recent scientific research. A clinical case of diagnosis of this rare disease is given.