Radiographic features of pulmonary tuberculosis in HIV-infected patients with different severity of immunosuppression and deviant behavior
https://doi.org/10.18093/0869-0189-2018-28-2-211-216
Abstract
The objective of this study was to investigate radiological features of pulmonary tuberculosis in HIV-infected patients with different severity of immunosuppression and deviant behavior. Methods. This was a single-center total observational retrospective study. The study involved 257 patients with pulmonary tuberculosis and NIV-infection who was treated and followed at a penitentiary tuberculosis hospital. Results. Tuberculosis-associated lung lesions were diagnosed in 94.2% of patients. Extrapulmonary and generalized tuberculosis increased with worsening immunity. Majority of patients were 20 – 29 and 30 – 39 years old. Typical radiological features included lung root lesions due to hilar lymph node enlargement in patients with CD4 lymphocytes < 100 cells/µL. CD4 lymphocytes decrease < 100 cells/µL was more likely in patients with involvement of ≥ 3 lung lobes and less likely in patients with involvement of 1 or 2 lung segments. CD4 lymphocytes decrease < 100 cells/µL was associated with prominent lung tissue infiltration (39.0%); moderate infiltration of the lung tissue did not depend on immunosuppression. Cavitation ≤ 2 cm was frequent (76.9 – 96.0%), mostly in the right lung (36.4 – 53.8%) and did not depend on immunosuppression. Conclusion. The most prevalent pulmonary tuberculosis in HIV-infected patients was infiltrative tuberculosis independently on CD4 lymphocyte number.
About the Author
V. S. Borovitskiy
Branch Tuberculosis Hospital, Medical Unit No.43, Federal Penitentiary Service of Russian Federation
Russian Federation
Candidate of Medicine, phthisiatrician
Russian Federation
Candidate of Medicine, phthisiatrician
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For citations:
Borovitskiy V.S. Radiographic features of pulmonary tuberculosis in HIV-infected patients with different severity of immunosuppression and deviant behavior. PULMONOLOGIYA. 2018;28(2):211-216. (In Russ.) https://doi.org/10.18093/0869-0189-2018-28-2-211-216
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