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Pharmacoeconomic assessment of dual bronchodilation therapy in patients with COPD

https://doi.org/10.18093/0869-0189-2018-28-1-61-68

Abstract

This study was aimed at clinical and economic assessment of feasibility of inclusion glycopyrronium bromide/indacaterol fixed combination in the State Program for providing necessary drugs to patients. Methods. This retrospective study was based on previously published clinical data. Change of economic burden was assessed using budget impact analysis. Cost-efficacy was assessed using cost minimization analysis and lost opportunities analysis. Results. Switching COPD patients from free combination of long-acting bronchodilators (LABD) to glycopyrronium bromide/indacaterol fixed combination has led to 20.44% decrease in the economic burden. The 3-year cost reduction of COPD therapy has reached RUB 2,416 bln. Conclusion. The results demonstrated higher cost-efficacy of glycopyrronium bromide/indacaterol fixed combination compared to the standard therapy of COPD. Inclusion of glycopyrronium bromide/indacaterol combination into the State Program for providing necessary drugs to COPD patients could be rational and ecomonically feasible.

About the Authors

S. K. Zyryanov
The Peoples' Friendship University of Russia (Medical University).
Russian Federation

Sergey K. Zyryanov, Doctor of Medicine, Professor, Head of Department of General and Clinical Pharmacology.

ul. Miklukho-Maklaya 6, Moscow, 117198.



I. N. D'yakov
I.I.Mechnikov Federal Research Vaccine and Serum Institute, Russian Academy of Science; Independent Non-commercial Organization “Research and Practical Center for Investigation of Issues of Rational Pharmacotherapy and Pharmacoeconomics”.
Russian Federation

Il'ya N. D'yakov, Candidate of Medicine, Head of Laboratory of Biosynthesis of Immunoglobulines.

: Malyy Kazennyy per. 5A, Moscow, 105064; ul. Aviamotornaya 50, build. 2, Moscow, 111024.



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Review

For citations:


Zyryanov S.K., D'yakov I.N. Pharmacoeconomic assessment of dual bronchodilation therapy in patients with COPD. PULMONOLOGIYA. 2018;28(1):61-68. (In Russ.) https://doi.org/10.18093/0869-0189-2018-28-1-61-68

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)