Gender aspects of natural course of asthma
https://doi.org/10.18093/0869-0189-2017-27-6-781-788
Abstract
Published studies on gender aspects of the natural course of asthma are controversial and do not give information on gender difference of asthma. However, most studies showed a gradual increase in prevalence of asthma symptoms and morbidity in girls. Gender difference in asthma course was shown in several studies. In patients older 40 years, asthma was confirmed in women significantly more often. Female gender was shown to be an independent risk factor of non-allergic asthma. Natural course of asthma in females was more severe than in males. Gender difference is also related to a rate of hospitalization due to asthma. Hospitalizations due to asthma and need in reliever medications are more often in boys younger 12 years and in girls after puberty. This tendency maintains in adults.
According to this review, one can conclude that gender difference in the natural course of asthma appears in puberty and could be explained by gender difference in anatomy of the airways and endocrine system that could lead to more prominent bronchial hyperreactivity and, as a result, worse asthma control.
About the Authors
O. S. Kobyakova
Siberian State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Ol'ga S. Kobyakova, Doctor of Medicine, Professor, Head of Department of General Practice and Outpatient Therapy
Moskovskiy tract 2, Tomsk, 634050, Russia
E. S. Kulikov
Siberian State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Evgeniy S. Kulikov, Associate Professor, Department of General Practice and Outpatient Therapy
Moskovskiy tract 2, Tomsk, 634050, Russia
I. A. Deev
Siberian State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Ivan A. Deev, Doctor of Medicine, Professor, Department of General Pediatric Diseases with Course in Pediatric Diseases, Therapeutic Faculty
Moskovskiy tract 2, Tomsk, 634050, Russia
I. D. Pimenov
Siberian State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Igor' D. Pimenov, Resident Physician, Department of General Practice and Outpatient Therapy
Moskovskiy tract 2, Tomsk, 634050, Russia
I. L. Kolomeets
Siberian State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Ivan L. Kolomeets, Postgraduate student, Department of General Pediatric Diseases with Course in Pediatric Diseases, Therapeutic Faculty
Moskovskiy tract 2, Tomsk, 634050, Russia
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Review
For citations:
Kobyakova O.S., Kulikov E.S., Deev I.A., Pimenov I.D., Kolomeets I.L. Gender aspects of natural course of asthma. PULMONOLOGIYA. 2017;27(6):781-788. (In Russ.) https://doi.org/10.18093/0869-0189-2017-27-6-781-788
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