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Clinical features of interstitial lung diseases according to data from the Irkutsk Register

https://doi.org/10.18093/0869-0189-2017-27-6-740-747

Abstract

The aim of the study was to investigate clinical features of interstitial lung diseases (ILD) using data from the register of Irkutsk residents with ILD. Methods. Medical history, clinical and functional data and data of high-resolution computed tomography (HRCT) of the lungs of 110 patients (67 women, 43 men, mean age, 56.2 ± 15.9 years) were analyzed. Lung biopsy was performed in 49 patients (45%). Results. Bilateral slowly resolving and/or recurrent pneumonia, unexplained pulmonary dissemination and idiopathic pulmonary fibrosis were the most frequent referral diagnoses. After thorough examination, three groups of ILDs were diagnosed most often: ILD with a known cause (32%), idiopathic interstitial pneumonias (30%), and pulmonary sarcoidosis (29%). Cough and dyspnea were the leading symptoms at ILD onset (in 48% and 39% of patients, respectively). The average duration of respiratory symptoms was 29.5 ± 33.0 months. Asymptomatic radiological abnormalities were the only reason for diagnostic work-up in 13% of the patients. Conclusion. Diagnosis of ILD is quite challenging for primary care physicians and pulmonologists. Accuracy and timeliness of diagnosis of ILD requires multidisciplinary approach as far as depends on quality of diagnostic procedures including medical history, lung auscultation, lung function testing, HRCT, and morphological examination, but also on the physician’s awareness and clinical experience.

About the Authors

M. C. Nashatyreva
Irkutsk City Teaching Hospital No.1
Russian Federation

Mariya S. Nashatyreva, pulmonologist 

ul. Baykal'ska 118, Irkutsk, 664046, Russia



I. N. Trofimenko
Irkutsk State Medical Academy of Postgraduate Training
Russian Federation

Irina N. Trofimenko, Doctor of Medicine, Associate Professor, Department of Clinical Allergology and Pulmonology 

mkr Yubileynyy 100, Irkutsk, 664079, Russia



B. A. Chernyak
Irkutsk State Medical Academy of Postgraduate Training
Russian Federation

Boris A. Chernyak, Doctor of Medicine, Professor, Head of Department of Clinical Allergology and Pulmonology 

mkr Yubileynyy 100, Irkutsk, 664079, Russia



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Review

For citations:


Nashatyreva M.C., Trofimenko I.N., Chernyak B.A. Clinical features of interstitial lung diseases according to data from the Irkutsk Register. PULMONOLOGIYA. 2017;27(6):740-747. (In Russ.) https://doi.org/10.18093/0869-0189-2017-27-6-740-747

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)