Bronchial asthma and upper gastrointestinal tract: clinical parallels
https://doi.org/10.18093/0869-0189-2017-27-5-629-635
Abstract
The aim of this study was to evaluate the upper gastrointestinal tract in patients with asthma and to investigate relationships between the diagnosed digestive abnormalities and asthma course.
Methods. Asthma clinical signs, bronchial obstruction, severity of inflammation, immunological reactivity, and endoscopic characteristics of esophagus, stomach, and duodenum were studied in patients with asthma and comorbid diseases of the upper gastrointestinal tract (the study group; n = 124) and in patients with asthma without clinical signs of digestive disease (the comparator group; n = 23).
Results. Asthma course, inflammation and immunological abnormalities were more severe in patients with digestive disorders. Inflammation, atrophy and gastrointestinal motility changes were seen during endoscopy.
Conclusion. These abnormalities were related to clinical features of asthma, severity of bronchial inflammation and immunological disorders.
About the Authors
T. N. Zaripova
Siberian Federal State Scientific and Clinical Center, Federal Medical and Biological Agency
Russian Federation
Russian Federation
Doctor of Medicine, Professor, Leading Researcher, Therapeutic Department, Branch of Tomsk Research Institute of Balneology and Physiotherapy
tel.: (913) 812-34-86
ul. Mira, 4; Seversk, Tomsk region, 636035, Russia
I. I. Antipova
Siberian Federal State Scientific and Clinical Center, Federal Medical and Biological Agency
Russian Federation
Russian Federation
Candidate of Medicine, Leading Researcher, Therapeutic Department, Branch of Tomsk Research Institute of Balneology and Physiotherapy
tel.: (913) 828-84-09
ul. Mira, 4; Seversk, Tomsk region, 636035, Russia
N. M. Yur'eva
Siberian Federal State Scientific and Clinical Center, Federal Medical and Biological Agency
Russian Federation
Russian Federation
Hospital Chief Executive Officer, Branch of Tomsk Research Institute of Balneology and Physiotherapy
tel.: (909) 541-01-42
ul. Mira, 4; Seversk, Tomsk region, 636035, Russia
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Review
For citations:
Zaripova T.N., Antipova I.I., Yur'eva N.M. Bronchial asthma and upper gastrointestinal tract: clinical parallels. PULMONOLOGIYA. 2017;27(5):629-635. (In Russ.) https://doi.org/10.18093/0869-0189-2017-27-5-629-635
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