Mobile cardiorespiratory and metabolic laboratory: diagnosis of chronic obstructive pulmonary disease, cardiovascular and metabolic diseases
https://doi.org/10.18093/0869-0189-2016-26-2-215-221
Abstract
The aim of this study was to determine risk factors of chronic non-infectious diseases and early diagnosis of cardiovascular, respiratory and endocrine functional disorders in industrial workers using a mobile cardiorespiratory and metabolic laboratory. Methods. This was a prospective non-comparative observational study in a non-selected population. All participants underwent the following measurements: weight and height, wrist and thigh circumferences, pulse oxymetry, exhaled nitric oxide (NO) and exhaled carbon monooxide (CO), spirometry before and after bronchodilator inhalation, electrocardiogram, arterial stiffness and endothelial dysfunction, blood glucose and blood total cholesterol. Indirect calorimetry with energy expenditure calculation was used in several patients. Validated questionnaires were also used. Results. The study involved 194 industrial workers. High prevalence of risk factors, such as tobacco smoking (45% of active smokers, 31% of ex-smokers), obesity (BMI ≥ 30 kg x m–2 in 37%), hypercholesterolemia (34%), and endothelial dysfunction (57%), was found. Vascular biomechanics correlated with bronchial patency, systemic arterial pressure and exhaled CO concentration. Bronchial obstruction was found in 56% of subjects, of them, COPD was diagnosed in 13%. Conclusion. Mobile cardiorespiratory and metabolic laboratory allows medical care delivery directly to a working place, and effective detection of risk factors and chronic lung disease.
About the Authors
S. Z. Batyn
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia: 32, build. 4, 11th Parkovaya str., Moscow, 105077, Russia;
Russian Federation
Russian Federation
PhD, Senior Researcher at Laboratory of Intensive Care and Respiratory Failure, Head of Organisational and Methodological Group, Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; tel.: (495) 465-52-64;
A. V. Chernyak
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia: 32, build. 4, 11th Parkovaya str., Moscow, 105077, Russia;
Russian Federation
Russian Federation
PhD, Head of Laboratory of Functional and Ultra-sound Investigations; Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; tel.: (495) 465-53-84;
G. V. Neklyudova
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia: 32, build. 4, 11th Parkovaya str., Moscow, 105077, Russia;
Russian Federation
Russian Federation
MD, Chief Scientist at Laboratory of Functional and Ultra-sound Investigations; Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; tel.: (495) 465-53-84;
Zh. K. Naumenko
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia: 32, build. 4, 11th Parkovaya str., Moscow, 105077, Russia;
Russian Federation
Russian Federation
PhD, Senior Researcher at Laboratory of Functional and Ultrasound Investigations, Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; tel.: (495) 465 53 84;
E. A. Ermakova
State Institution «Russian Medical Postgraduate Academy», Healthcare Ministry of Russia: 2/1 Barrikadnaya str., Moscow, 123995, Russia;
Russian Federation
Russian Federation
PhD student at Department of Endocrinology and Diabetology, State Institution «Russian Medical Postgraduate Academy», Healthcare Ministry of Russia; tel.: (499) 252-21-04
V. A. Shtabnitskiy
State Institution «N.I.Pirogov Russian National Research Medical University», Healthcare Ministry of Russia: 1 Ostrovityanova str., Moscow, 117997, Russia
Russian Federation
Russian Federation
PhD, Assistant Lecturer at Department of Hospital Internal Medicine, Pediatric Faculty, State Institution «N.I.Pirogov Russian National Research Medical University», Healthcare Ministry of Russia; Junior Researcher at the Laboratory of Clinical Pharmacology, Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; tel.: (495) 465-52-64;
Z. R. Aysanov
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia: 32, build. 4, 11th Parkovaya str., Moscow, 105077, Russia;
Russian Federation
Russian Federation
MD, Professor, Head of Division of Clinical Physiology and Clinical Trials, Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; tel.: (495) 465-53-84;
A. G. Chuchalin
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia: 32, build. 4, 11th Parkovaya str., Moscow, 105077, Russia;
Russian Federation
Russian Federation
MD, Professor, Academician of Russian Science Academy, Director of Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia;
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Review
For citations:
Batyn S.Z., Chernyak A.V., Neklyudova G.V., Naumenko Zh.K., Ermakova E.A., Shtabnitskiy V.A., Aysanov Z.R., Chuchalin A.G. Mobile cardiorespiratory and metabolic laboratory: diagnosis of chronic obstructive pulmonary disease, cardiovascular and metabolic diseases. PULMONOLOGIYA. 2016;26(2):215-221. (In Russ.) https://doi.org/10.18093/0869-0189-2016-26-2-215-221
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