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PULMONOLOGIYA

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A case of successful surgical treatment of reflux-associated bronchial asthma

https://doi.org/10.18093/0869-0189-2015-25-6-757-762

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Abstract

Pathogenic relationship between gastrooesophageal reflux disease (GORD) and bronchial asthma (BA) includes local and general mechanisms. One of basic local mechanisms is microaspiration of gastric content to the bronchial tree. Small intestine bacterial overgrowth (SIBO) syndrome can cause general sensitization and supports immune inflammation in the intestinal mucosa. A 50yearold female with BA underwent surgery for GORD resulted in complete elimination of GORD and improvement in BA course. Thus, ileocecal valve dysfunction and chronic duodenum motility disorder are important pathogenic factors of BA. Adequate correction of these conditions, such as ileocecal valve correction and duodenoje junostomy, seem to be a perspective methods for treatment of GORDassociated BA.

For citations:


Martynov V.L., Khayrdinov A.Kh., Kazarina N.V. A case of successful surgical treatment of reflux-associated bronchial asthma. PULMONOLOGIYA. 2015;25(6):757-762. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-6-757-762

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)