A case of successful surgical treatment of reflux-associated bronchial asthma
https://doi.org/10.18093/0869-0189-2015-25-6-757-762
Abstract
Pathogenic relationship between gastrooesophageal reflux disease (GORD) and bronchial asthma (BA) includes local and general mechanisms. One of basic local mechanisms is microaspiration of gastric content to the bronchial tree. Small intestine bacterial overgrowth (SIBO) syndrome can cause general sensitization and supports immune inflammation in the intestinal mucosa. A 50yearold female with BA underwent surgery for GORD resulted in complete elimination of GORD and improvement in BA course. Thus, ileocecal valve dysfunction and chronic duodenum motility disorder are important pathogenic factors of BA. Adequate correction of these conditions, such as ileocecal valve correction and duodenoje junostomy, seem to be a perspective methods for treatment of GORDassociated BA.
About the Authors
V. L. Martynov
Nizhniy Novgorod State City Clinical Hospital N12: 8, Pavla Mochalova str., Nizhniy Novgorod, 603003, Russia
Russian Federation
Russian Federation
MD, Assistant Professor, Professor at Department of Surgery, Nizhniy Novgorod State City Clinical Hospital N 12; tel.: (831) 2256629
A. Kh. Khayrdinov
Nizhniy Novgorod State City Clinical Hospital N12: 8, Pavla Mochalova str., Nizhniy Novgorod, 603003, Russia
Russian Federation
Russian Federation
Surgeon at Surgical Department, Nizhniy Novgorod State City Clinical Hospital N 12; tel.: (831) 2256629
N. V. Kazarina
Nizhniy Novgorod State City Clinical Hospital N12: 8, Pavla Mochalova str., Nizhniy Novgorod, 603003, Russia
Russian Federation
Russian Federation
Attending Physician at Surgical Department, Nizhniy Novgorod State City Clinical Hospital N 12; tel.: (831) 2256629
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Review
For citations:
Martynov V.L., Khayrdinov A.Kh., Kazarina N.V. A case of successful surgical treatment of reflux-associated bronchial asthma. PULMONOLOGIYA. 2015;25(6):757-762. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-6-757-762
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