Новые перспективы в лечении хронической обструктивной болезни легких: в фокусе – аклидиния бромид


https://doi.org/10.18093/0869-0189-2015-25-6-725-735

Полный текст:


Аннотация

Аклидиний – новый антихолинергический препарат, предназначенный для поддерживающей терапии хронической обструктивной болезни легких (ХОБЛ). Аклидиний имеет ряд фармакокинетических особенностей, определяющих его высокий профиль безопасности и крайне низкий риск развития внелегочных побочных эффектов. В клинических исследованиях III фазы продемонстрировано, что при использовании аклидиния достоверно улучшаются функциональные показатели, уменьшается тяжесть клинических симптомов заболевания и повышается качество жизни у пациентов с ХОБЛ. В данном обзоре представлены имеющиеся на сегодня литературные данные об особенностях фармакокинетики, клинической эффективности и безопасности аклидиния.


Об авторах

С. Н. Авдеев
ФГБУ «НИИ пульмонологии» ФМБА России: 105077, Москва, ул. 11-я Парковая, 32, корп. 4
Россия

д. м. н., профессор, руководитель клинического отдела ФГБУ «НИИ пульмонологии» ФМБА России; тел. / факс: (495) 4655264



Н. В. Трушенко
ФГБУ «НИИ пульмонологии» ФМБА России: 105077, Москва, ул. 11-я Парковая, 32, корп. 4
Россия

к. м. н., научный сотрудник клинического отдела ФГБУ «НИИ пульмонологии» ФМБА России; тел. / факс: (495) 4655264



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Дополнительные файлы

Для цитирования: Авдеев С.Н., Трушенко Н.В. Новые перспективы в лечении хронической обструктивной болезни легких: в фокусе – аклидиния бромид.  Пульмонология. 2015;25(6):725-735. https://doi.org/10.18093/0869-0189-2015-25-6-725-735

For citation: Avdeev S.N., Trushenko N.V. New perspectives in therapy of chronic obstructive pulmonary disease: revolving around aclidinium bromide. Russian Pulmonology. 2015;25(6):725-735. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-6-725-735

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)