Glomerular filtration rate in different phenotypes of bronchial asthma
https://doi.org/10.18093/0869-0189-2015-25-5-593-599
Abstract
The aim of the study was to estimate the glomerular filtration rate (eGFR) in patients with different phenotypes of bronchial asthma (BA).
Material and methods. One hundred and three patients with different BA phenotypes were involved. eGFR was estimated using CKDEPI equation.
Results. eGFR was significantly lower in patients with nonatopic and aspirininduced BA compared to allergic BA patients who had eGFR was within normal range. eGFR was also reduced in BA patients regularly treated with oral steroids but this difference did not reach statistical significance. A number of significant relationships pertinent to eGFR was found in patients with allergic BA; no relationships with eGFR were found in BA patients at regular therapy with oral steroids.
Conclusion. The results rise possible effect of BA pathogenic pathways on the renal function, and vise versa.
About the Authors
V. N. Mineev
Academician I.P.Pavlov First Saint&Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint&Petersburg, 197022, Russia
Russian Federation
Russian Federation
MD, Professor at M.V.Chernorutskiy Department of Hospital Internal Medicine, Academician I.P.Pavlov First Saint Petersburg State Medical University, Healthcare Ministry of Russia, tel.: (812) 4507163
Z. A. Zelenkova
Academician I.P.Pavlov First Saint&Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint&Petersburg, 197022, Russia
Russian Federation
Russian Federation
Junior Physician at M.V.Chernorutskiy Department of Hospital Internal Medicine, Academician I.P.Pavlov First SaintPetersburg State Medical University, Healthcare Ministry of Russia, tel.: (921) 3780565
O. M. Sadovnikova
Academician I.P.Pavlov First Saint&Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint&Petersburg, 197022, Russia
Russian Federation
Russian Federation
the 5thyear student of Medical Faculty, Academician I.P.Pavlov First SaintPetersburg State Medical University, Healthcare Ministry of Russia, tel.: (953) 3453204
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Review
For citations:
Mineev V.N., Zelenkova Z.A., Sadovnikova O.M. Glomerular filtration rate in different phenotypes of bronchial asthma. PULMONOLOGIYA. 2015;25(5):593-599. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-5-593-599
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