Economic efficacy of vaccination of patients with chronic obstructive pulmonary disease and coronary heart disease
https://doi.org/10.18093/0869-0189-2015-25-3-312-319
Abstract
The aim of this study was prospective evaluation of clinical and economic efficacy of vaccination with conjugate pneumococcal vaccine PCV13 in patients with chronic obstructive pulmonary disease (COPD) and with comorbidity of COPD and coronary heart disease (CHD) during two consecutive years. Methods. The study involved 306 male patients (mean age, 62.09 ± 9.22 yrs). Clinical and laboratory examination was performed in all patients. Dyspnea was assessed using MRC scale. Hospitalisation rate related to COPD exacerbation and number of pneumonia were analyzed. Patients were vaccinated with PCV13. The study was conducted in 2012–2014. Results. COPD exacerbation rate became 8 times lower and hospitalisation rate became 4 times lower after vaccination in patients with comorbidity of COPD and CHD. Healthcare cost saving was 64% in one year after vaccination and 70% in 1.5 years after vaccination. Healthcare cost saving in patients with comorbidity of COPD and CHD was 82.1% in two years. On contrary, effect of vaccination with PPV23 declined with time; the healthcare cost saving was 55% and 47% in 1 year and 1.5 years after vaccination, respectively. Conclusion. Vaccination of patients with COPD and CHD using pneumococcal vaccine PCV13 could reduce healthcare costs.
About the Authors
G. L. Ignatova
State Institution “Chelyabinsk State Medical Academy”, Healthcare Ministry of Russia: 64, Vorovskogo str., Chelyabinsk, 454092, Russia
Russian Federation
Russian Federation
MD, Professor, Head of Department of Therapy, Faculty of Postgraduate Physician Training, State Institution “Chelyabinsk State Medical Academy”, Healthcare Ministry of Russia; tel.: (351) 742-66-40;
V. N. Antonov
State Institution “Chelyabinsk State Medical Academy”, Healthcare Ministry of Russia: 64, Vorovskogo str., Chelyabinsk, 454092, Russia
Russian Federation
Russian Federation
PhD, Associate Professor, Department of Therapy, Faculty of Postgraduate Physician Training, State Institution “Chelyabinsk State Medical Academy”, Healthcare Ministry of Russia; tel.: (351) 742-66-40;
O. V. Rodionova
State Institution “Chelyabinsk State Medical Academy”, Healthcare Ministry of Russia: 64, Vorovskogo str., Chelyabinsk, 454092, Russia
Russian Federation
Russian Federation
PhD, Associate Professor, Department of Therapy, Faculty of Postgraduate Physician Training, State Institution “Chelyabinsk State Medical Academy”, Healthcare Ministry of Russia; tel.: (351) 742-66-40;
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Review
For citations:
Ignatova G.L., Antonov V.N., Rodionova O.V. Economic efficacy of vaccination of patients with chronic obstructive pulmonary disease and coronary heart disease. PULMONOLOGIYA. 2015;25(3):312-319. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-3-312-319
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