Depression in patients with chronic obstructive pulmonary disease and effects of pulmonary rehabilitation
https://doi.org/10.18093/0869-0189-2015-25-1-64-67
Abstract
Pulmonary rehabilitation is one of ways to improve systemic features of chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate depressive disorders in patients with severe COPD and to evaluate effects of pulmonary rehabilitation. Methods. The study involved 47 patients with severe COPD. Of them, 26 patients were treated with the standard therapy and physical rehabilitation and 21 patients were treated with the standard therapy only. The CES-D questionnaire was used to diagnose depressive disorders. The MOS SF-36 questionnaire was used to evaluate quality of life. Interleukin-6 (IL-6) as a marker of systemic inflammation was measured in blood. Results. According to results of questioning, severe depression was found in 29.2 % of patients, moderate depression was in 33.3 %, mild depression was in 25 %; 12.5 % of the patients did not have depressive disorders. Depressive symptoms were less prominent (scored as 17.4 ± 6.3 vs 26.8 ± 10.2 that corresponds to the absence of depression) in the patient group involved in a physical training programme. Depression was related to IL-6 blood level and quality of life. Conclusion. Physical rehabilitation could reduce systemic inflammation and depressive disorders in patients with severe COPD.
About the Authors
N. N. Meshcheryakova
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; 32, build. 4, 11th Parkovaya ul., Moscow, 105077, Russia;
Russian Federation
Russian Federation
PhD, Senior Researcher of Federal Institution "Pulmonology Research Institute", Federal Medical and Biological Agency of Russia; tel.: (903) 744-24-63;
A. S. Belevskiy
State Institution «N.I.Pirogov Russian National Research Medical University», Healthcare Ministry of Russia: 1, Ostrovityanova ul., Moscow, 117997, Russia
Russian Federation
Russian Federation
MD, Professor of Department of Pulmonology, Faculty of Postgraduate Physician Training, State Institution "N.I.Pirogov Russian National Research Medical University", Healthcare Ministry of Russia; tel.: (495) 963-24-67;
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Review
For citations:
Meshcheryakova N.N., Belevskiy A.S. Depression in patients with chronic obstructive pulmonary disease and effects of pulmonary rehabilitation. PULMONOLOGIYA. 2015;25(1):64-67. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-1-64-67
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