Бронхиальная астма и ожирение: поиск терапевтических моделей
Аннотация
Все большее внимание экспертов уделяется фенотип-обоснованному подходу к лечению пациентов с бронхиальной астмой (БА). Одним из основных клинических фенотипов является сочетание БА и избыточной массы тела, а в некоторых случаях – ожирения. Ряд клинических особенностей этого тандема объясняется результатами молекулярно-генетических исследований. Активный поиск взаимосвязей между фенотипом, генотипом и механизмом развития заболевания позволит разработать эффективный терапевтический алгоритм, наиболее прогностически оправданный у данной подгруппы пациентов.
Об авторах
Д. С. Фомина
ГБОУ ДПО "Российская медицинская академия последипломного образования" Минздрава России: 125993, Москва, ул. Баррикадная, 2 / 1
ГБУЗ "Городская клиническая больница No52" Департамента здравоохранения Москвы: 123182, Москва, ул. Пехотная, 3
Россия
Россия
к. м. н., доцент кафедры клинической аллергологии ГБОУ ДПО "Российская медицинская академия последипломного образования" Минздрава России, зав. аллергологическим отделением ГБУЗ "Городская клиническая больница No 52" ДЗ Москвы; тел.: (499) 196-19-54
Л. А. Горячкина
ГБОУ ДПО "Российская медицинская академия последипломного образования" Минздрава России: 125993, Москва, ул. Баррикадная, 2 / 1
Россия
Россия
д. м. н., профессор, зав. кафедрой клинической аллергологии ГБОУ ДПО "Российская медицинская академия последипломного образования" Минздрава России; тел.: (499) 196-19-54
Ю. Г. Алексеева
ГБУЗ "Городская клиническая больница No52" Департамента здравоохранения Москвы: 123182, Москва, ул. Пехотная, 3
Россия
Россия
врач аллерголог-иммунолог ГБУЗ "Городская клиническая больница No 52" ДЗ Москвы; тел.: (499) 196-29-88
Е. Н. Бобрикова
ГБУЗ "Филиал No2 Городская поликлиника No62" Департамента здравоохранения Москвы: 125083, Москва, ул. Юннатов, 12
Россия
Россия
врач аллерголог-иммунолог ГБУЗ "Филиал No 2 Городская поликлиника No 62" ДЗ Москвы, главный внештатный аллерголог САО Москвы; тел.: (962) 962-00-96
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Для цитирования:
Фомина Д.С., Горячкина Л.А., Алексеева Ю.Г., Бобрикова Е.Н. Бронхиальная астма и ожирение: поиск терапевтических моделей. Пульмонология. 2014;(6):94-102. https://doi.org/10.18093/0869-0189-2014-0-6-94-102
For citation:
Fomina D.S., Goryachkina L.A., Alekseeva Y.G., Bobrikova E.N. Bronchial asthma and obesity: search for therapeutic models. Russian Pulmonology. 2014;(6):94-102. (In Russ.) https://doi.org/10.18093/0869-0189-2014-0-6-94-102
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