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A patient with hemoptysis and kidney damage: clinical challenge

https://doi.org/10.18093/0869-0189-2025-35-1-125-129-135-137

Abstract

The article describes a clinical case of pulmonary-renal syndrome in a 41-year-old man. A brief review of the scientific literature is presented together with the discussion of the differential diagnosis and the diagnostic features. It is important to remember that pulmonary-renal syndrome combines diffuse alveolar hemorrhage and glomerulonephritis and is a life-threatening condition with the development of acute renal injury and possible pulmonary bleeding which can lead to death.

About the Authors

E. V. Bobkov
Federal State Autonomous Educational Institution of Higher Education “N.I.Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation
Russian Federation

Evgeny V. Bobkov, Сandidate of Medicine, Associate Professor, Department of Hospital Therapy of the Pediatric Faculty

ul. Ostrovityanova 1, Moscow, 117997, tel.: (499) 780-08-5 


Competing Interests:

The authors declare that there is no conflict of interest. 



O. N. Brodskaya
Federal State Autonomous Educational Institution of Higher Education “N.I.Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation
Russian Federation

Olga N. Brodskaya, Сandidate of Medicine, Associate Professor, Department of Hospital Therapy of the Pediatric Faculty

ul. Ostrovityanova 1, Moscow, 117997, tel.: (499) 780-08-50 


Competing Interests:

The authors declare that there is no conflict of interest. 



D. Yu. Gripas
Federal State Autonomous Educational Institution of Higher Education “N.I.Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation
Russian Federation

Daria Yu. Gripas, VI year Student 

ul. Ostrovityanova 1, Moscow, 117997, tel.: (985) 452-37-52


Competing Interests:

The authors declare that there is no conflict of interest. 



References

1. O’Gurek D., Choi, H.Y.J. Hemoptysis: evaluation and management. Am. Fam. Physician. 2022; 105 (2): 144–151. Available at: https://www.binasss.sa.cr/mar22/5.pdf

2. Anaev E.K., Baranova I.A., Belevsky A.S. [Pulmonary vasculitis: diagnosis and treatment]. Terapevticheskiy arkhiv. 2018; 90 (3): 99–106. DOI: 10.26442/terarkh201890399-106 (in Russian).

3. Il’kovich M.M. [Diffuse parenchymal lung diseases]. Moscow: GEOTAR-Media; 2021. DOI: 10.33029/9704-5908-9-DPL-2021-1-440 (in Russian).

4. Bayrashevskaya A.V., Degtyareva N.D., Radenska-Lopovok S.G. [ANCA-associated small-vessel vasculitides]. Arkhiv patologii. 2022; 84 (1): 50–58. DOI: 10.17116/patol20228401150 (in Russian).

5. Ross C., Makhzoum J. P., Pagnoux C. Updates in ANCA-associated vasculitis. Eur. J. Rheumatol. 2022; 9 (3): 153–166. DOI: 10.5152/eujrheum.2022.20248.

6. Boyle N., O’Callaghan M., Ataya A. et al. Pulmonary renal syndrome: a clinical review. Breathe (Sheff.). 2022; 18 (4): 220208. DOI: 10.1183/20734735.0208-2022.

7. Reggiani F., L’Imperio V., Calatroni M. et al. Goodpasture syndrome and anti-glomerular basement membrane disease. Clin. Exp. Rheumatol. 2023; 41 (4): 964–974. DOI: 10.55563/clinexprheumatol/tep3k5.

8. Puéchal X. Granulomatosis with polyangiitis (Wegener’s). Joint Bone Spine. 2020; 87 (6): 572–578. DOI: 10.1016/j.jbspin.2020.06.005.

9. Pyo J.Y., Lee L.E., Park Y.B., Lee S.W. Comparison of the 2022 ACR/EULAR classification criteria for antineutrophil cytoplasmic antibody-associated vasculitis with previous criteria. Yonsei Med. J. 2023; 64 (1): 11–17. DOI: 10.3349/ymj.2022.0435.

10. Sada K.E., Yamamura M., Harigai M. et al. Classification and characteristics of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis in a nationwide, prospective, inception cohort study. Arthritis Res. Ther. 2014; 16 (2): R101. DOI: 10.1186/ar4550.

11. Robson J.C., Grayson P.C., Ponte C. et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis. Ann. Rheum. Dis. 2022; 81 (3): 315–320. DOI: 10.1136/annrheumdis-2021-221795.

12. Suppiah R., Robson J.C., Grayson P.C. et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis. Ann. Rheum. Dis. 2022; 81 (3): 321–326. DOI: 10.1136/annrheumdis-2021-221796.

13. Grayson P.C., Ponte C., Suppiah R. et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for eosinophilic granulomatosis with polyangiitis. Ann. Rheum. Dis. 2022; 81 (3): 309–314. DOI: 10.1136/annrheumdis-2021-221794.

14. Kitching A.R., Hutchinson P., Atkins R.C., Holdsworth SR. The role of flow cytometric ANCA detection in screening for acute pauci-immune crescentic glomerulonephritis. Nephrol. Dial. Transplant. 2004; 19 (2): 365–370. DOI: 10.1093/ndt/gfg553.

15. Association of Nephrologists of Russia. [Clinical recommendations: Kidney damage in ANCA-associated vasculitis (ANCA-associated glomerulonephritis)]. 2021. Available at: https://rusnephrology.org/wp-content/uploads/2021/02/ANCA.pdf (in Russian)


Review

For citations:


Bobkov E.V., Brodskaya O.N., Gripas D.Yu. A patient with hemoptysis and kidney damage: clinical challenge. PULMONOLOGIYA. 2025;35(1):125-129. (In Russ.) https://doi.org/10.18093/0869-0189-2025-35-1-125-129-135-137

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)