Легочная гиалинизирующаяся гранулема: обзор литературы и презентация случая

Легочная гиалинизирующаяся гранулема (ЛГГ) – патология чрезвычайно редкая. В настоящее время по всему миру описано около 170–200 случаев. Все случаи описаны в иностранной литературе, в отечественной – сообщений о данной патологии не встречалось. Этиология заболевания неизвестна. Рентгенологическая картина очень неспецифична, в дифференциально-диагностический ряд входят опухоли легкого и плевры, а также инфекционные процессы в легких. У заболевших пациентов отмечается длительное стабильное течение данной патологии, а к длительной стойкой ремиссии может приводить лечение глюкокортикостероидами.

Целью работы явилось информирование врачей-пульмонологов, терапевтов, торакальных хирургов, онкологов, инфекционистов о существовании ЛГГ, особенностях диагностики, клинического течения и вариантах лечения данной патологии.

Заключение. В силу своей редкости ЛГГ в клинической деятельности врача-специалиста может и не встретиться за всю профессиональную карьеру. Однако следует знать о ее существовании и включать в дифференциально-диагностический ряд при рентгенологическом выявлении очаговых и фокусных теней при исследовании органов грудной клетки. Возможно, это заболевание обусловлено различными иммуномедиаторными процессами, хотя его патогенез до сих пор остается неясным. Для морфологического подтверждения диагноза необходимо выполнять резекцию легкого с целью последующего гистологического исследования. Прогноз течения благоприятный, а при своевременно начатом лечении возможно существенно продлить период ремиссии.

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