Nosocomial pneumonia in the thanatogenesis of patients with severe non-pulmonary disease
https://doi.org/10.18093/0869-0189-2011-0-6-58-61
Abstract
Summary. A retrospective analysis of clinical, radiological, laboratory and postmortem findings of 74 cases of nosocomial pneumonia (13.8 % of 536 autopsies performed for 5 years) has been carried out. Seriously ill patients died of nosocomial pneumonia alone (28 cases, or 37.8 %) or of another primary disease (13 cases, or 17.6 %), or of their combination (33 cases, or 44.6 %) have been examined. Sixteen significant correlation links between clinical and laboratory parameters were found. This allowed evaluation of those parameters in term of therapeutic strategy and prognosis of nosocomial pneumonia. Bacterial colonization of pleural effusion and/or of pulmonary parenchyma was found in all the cases and was considered as a sign of immune suppression. This could provide rationale for development and implementation of preventive measures of nosocomial pneumonia in certain patients using vaccines or immune modulators.
About the Authors
I. I. Dantsig
Дорожная клиническая больница ОАО РЖД
Russian Federation
Russian Federation
I. M. Skipsky
ГОУ ВПО "Санкт-Петербургская государственная медицинская академия им. И.И.Мечникова"
Russian Federation
Russian Federation
N. F. Levin
Дорожная клиническая больница ОАО РЖД
Russian Federation
Russian Federation
A. P. Melnikova
ГБУЗ Ленинградской обл. "Бюро судебно-медицинской экспертизы"
Russian Federation
Russian Federation
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Review
For citations:
Dantsig I.I., Skipsky I.M., Levin N.F., Melnikova A.P. Nosocomial pneumonia in the thanatogenesis of patients with severe non-pulmonary disease. PULMONOLOGIYA. 2011;(6):58-61. (In Russ.) https://doi.org/10.18093/0869-0189-2011-0-6-58-61
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