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Posthypercapnic syndrome

https://doi.org/10.18093/0869-0189-2023-33-3-420-426

Abstract

Hypercapnic respiratory failure is a common cause of hospitalization and death in patients with chronic obstructive pulmonary disease (COPD).

The aim of this work was to analyze the pathophysiological mechanisms and clinical picture of hypercapnic respiratory failure and to discuss the tactics of managing a patient with COPD and posthypercapnic alkalosis that developed during treatment using a clinical case as an example.

Conclusion. To date, the search for new treatments for posthypercapnic alkalosis is still relevant, but there are few published studies on this topic. Acute problems in mixed metabolic disorders can be solved with an integrated therapeutic approach that includes the use of medical gases.

About the Authors

H. C. Nguyen
Federal State Autonomous Educational Institution of Higher Education “N.I. Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation
Russian Federation

Hoang Cuong Nguyen - Postgraduate student, Department of Hospital Therapy, Pediatric Faculty.

Ul. Ostrovityanova 1, Moscow, 117997; tel.: (967) 203-42-77


Competing Interests:

The authors report that there is no conflict of interest



I. A. Baranova
Federal State Autonomous Educational Institution of Higher Education “N.I. Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation
Russian Federation

Irina A. Baranova - Doctor of Medicine, Professor, Professor of Hospital Therapy Department, Pediatric Faculty.

Ul. Ostrovityanova 1, Moscow, 117997; tel.: (499) 780-08-16


Competing Interests:

The authors report that there is no conflict of interest



A. G. Chuchalin
Federal State Autonomous Educational Institution of Higher Education “N.I. Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation
Russian Federation

Alexander G. Chuchalin - Doctor of Medicine, Professor, Academician of Russian Academy of Sciences, Head of Department of Hospital Internal Medicine, Pediatric Faculty, N.I. Pirogov RNRMU; Chairman of the Executive Board of Russian Respiratory Society.

Ul. Ostrovityanova 1, Moscow, 117997; tel.: (499) 780-08-50


Competing Interests:

The authors report that there is no conflict of interest



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Supplementary files

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For citations:


Nguyen H., Baranova I.A., Chuchalin A.G. Posthypercapnic syndrome. PULMONOLOGIYA. 2023;33(3):420-426. (In Russ.) https://doi.org/10.18093/0869-0189-2023-33-3-420-426

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)