Smoke-related interstitial fibrosis – a case report
https://doi.org/10.18093/0869-0189-2022-32-4-626-630
Abstract
Smoking-related interstitial fibrosis (SRIF) is a recently described disease which is common finding in a long-term cigarette smokers.
Aim. To acquaint readers with relatively unknown interstitial disease. We describe a case of a smoking patient with a long smoking history and squamous cell carcinomas of the larynx and lung who complained of an unproductive cough, sore throat, hoarseness, difficulty in nasal breathing, and shortness of breath during exercise. Obstructive disorders, lung hyperinflation, and a severe decrease in diffusion capacity reflected the signs of severe emphysema in combination with fibrotic changes found by high resolution computed tomography (CT). X-ray picture and characteristic histological changes made it possible to diagnose SRIF.
Conclusion. Diagnostics of the disease should be based on CT-signs, histologic picture and functional data. The prognosis is relatively favorable.
About the Authors
M. V. Samsonova
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia; A. S. Loginov Moscow State Clinical and Research Center, Moscow Healthcare Department
Russian Federation
Competing Interests:
Russian Federation
Maria V. Samsonova, Doctor of Medicine, Head of Laboratory of Pathological Anatomy and Immunology, Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia, Senior Researcher, Laboratory of Pathomorphology, A. S. Loginov Moscow State Clinical and Research Center, Moscow Healthcare Department
Orekhovyy bul’var 28, Moscow, 115682
Shosse Entuziastov 86, Moscow, 111123
tel.: (495) 465-58-59
Competing Interests:
There is no conflict of interest.
K. Yu. Mikhailichenko
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia
Russian Federation
Competing Interests:
Russian Federation
Kirill Yu. Mikhajlichenko, Researcher, Pathology Department, Federal Pulmonology Research Institute
Orekhovyy bul’var 28, Moscow, 115682
tel.: (495) 465-58-59
Competing Interests:
There is no conflict of interest.
A. L. Cherniaev
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia; Federal State Budgetary Institution «A. P. Avtsyn Research Institute of Human Morphology»; Pirogov Russian National Research Medical University (Pirogov Medical University), Healthcare Ministry of Russia
Russian Federation
Competing Interests:
Russian Federation
Andrey L. Cherniaev, Doctor of Medicine, Head of the Department of Fundamental Pulmonology, Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia, Leading Researcher, Laboratory of Clinical Morphology, Avtsyn Research Institute оf Human Morphology оf Federal State Budgetary Scientific Institution “Petrovsky National Research Centre оf Surgery”, Professor, Department of Pathological Anatomy and Clinical Pathological Anatomy, Faculty of Medicine, Pirogov Russian National Research Medical University (Pirogov Medical University), Healthcare Ministry of Russia
Orekhovyy bul’var 28, Moscow, 115682
ul. Tsyurupy 3, Moscow, 117418
ul. Ostrovityanova 1, Moscow, 117997
tel.: (495) 465-58-59
Competing Interests:
There is no conflict of interest.
A. V. Chernyak
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia
Russian Federation
Competing Interests:
Russian Federation
Aleksandr V. Chernyak, Candidate of Medicine, Head of Laboratory of Functional and Ultra-sound Investigations, Federal Pulmonology Research Institute
Orekhovyy bul’var 28, Moscow, 115682
tel.: (465) 465-58-59
Competing Interests:
There is no conflict of interest.
N. A. Karchevskaya
N. V. Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department
Russian Federation
Competing Interests:
Russian Federation
Natal’ya A. Karchevskaya, Рulmonologist, Thoracic Surgical Department
Bolshaya Sukharevskaya pl. 3, Moscow, 129090
tel.: (495) 620-12-85
Competing Interests:
There is no conflict of interest.
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Review
For citations:
Samsonova M.V., Mikhailichenko K.Yu., Cherniaev A.L., Chernyak A.V., Karchevskaya N.A. Smoke-related interstitial fibrosis – a case report. PULMONOLOGIYA. 2022;32(4):626-630. (In Russ.) https://doi.org/10.18093/0869-0189-2022-32-4-626-630
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