Sepsis: multiple organ dysfunction syndrome in a patient with diabetes mellitus

Abstract

Aim. To demonstrate the course of sepsis and multiple organ dysfunction syndrome in a patient with decompensation of type 1 diabetes mellitus, to describe the applicable treatment. This case is relevant because of high mortality of patients with diabetes mellitus complicated by sepsis and multiple organ failure. The mortality is especially high when acute respiratory distress syndrome develops.

Results. The article presents a clinical case of a patient with diabetes mellitus complicated by acute kidney injury, hospital-acquired pneumonia, sepsis, and acute respiratory distress syndrome. The approach to treatment of multiple organ failure is also described.

Conclusion. Life support and intensive therapy (mechanical ventilation, regular tracheobronchial debridement, hemodiafiltration, and combined drug therapy, including drugs with hyaluronidase activity) led to successful resolution of sepsis in this patient.