Dynamics of quality of life in chronic obstructive bronchitis patients influenced by Salmeterol
Abstract
The randomized study was conducted evaluating an influence of Salmeterol (Serevent, Glaxo Wellcom) on quality of life in moderate chronic obstructive bronchitis patients. The assessment of quality of life was performed using the Respiratory questionnaire of Santa George hospital. The investigation included 2-week introductory period and 16-week treatment period. As a result the significant effect of Salmeterol on the principal parameters of the patients’ quality of life was found and the improvement in the quality of life exceeded the Salmeterol positive influence on bronchial passability parameters. The Salmeterol efficiency was not effected by a chronic bronchitis length. Meanwhile the smoking consumption and its intensity were combined with greater effect of Salmeterol on the quality of life.
About the Authors
E. I. Shmelev
ЦНИИ туберкулеза РАМН
Russian Federation
Russian Federation
N. M. Shmeleva
ЦНИИ туберкулеза РАМН
Russian Federation
Russian Federation
N. A. Didkovsky
НИИ иммунологии М3 РФ
Russian Federation
Russian Federation
I. A. Malashenkova
НИИ иммунологии М3 РФ
Russian Federation
Russian Federation
M. V. Beda
Медицинский отдел Представительства Глаксо Вэллком в России
Russian Federation
Russian Federation
N. M. Barmlcheyeva
НИИ физико-химической медицины
Russian Federation
Russian Federation
A. A. Peresetsky
НИИ физико-химической медицины
Russian Federation
Russian Federation
References
1. Шмелев Е.И. Хронический обструктивный бронхит / / Хроническая обструктивная болезнь легких / Под ред. А.Г.Чучалина.- М., 1998.- С.39-56.
2. Global Initiative for Chronic Obstructive Lung Disease.- Geneva: WHO, 2000.
3. Jones P.W. Quality of life measurement for patients with diseases of the airways / / Thorax.- 1991.- Vol.46, № 9.- P.676-682.
4. Jones P.W., Quirk F.H., Bareystock C.M., Littejohns P. A selfcomplete measure of health status for chronic air flow limitation - the St. George’s Respiratory Questionnaire / / Am. Rev. Respir. Dis. - 1992 - Vol.145, № 6.- P.1321-1327.
5. Jones P.W. Quality of life measurement; the value of standartization / / Eur. Respir. Rev.- 1997.- Vol.7, № 42.- P.46-49.
Review
For citations:
Shmelev E.I., Shmeleva N.M., Didkovsky N.A., Malashenkova I.A., Beda M.V., Barmlcheyeva N.M., Peresetsky A.A. Dynamics of quality of life in chronic obstructive bronchitis patients influenced by Salmeterol. PULMONOLOGIYA. 2000;(4):78-82. (In Russ.)
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