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A role of focal influence on cavity walls and near the cavity zone for increase the efficacy of treatment of destructive lung tuberculosis

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Abstract

Destructive lung tuberculosis is a heterogeneous group of various forms of the lung tuberculosis (recent, chronic, advanced) which have common features, such as the presence of cavities, a presence of Mycobacteria tuberculosis and they are hard for treatment. Peculiarities of the microcirculation, the fibrous capsule outside the cavity, the caseous and necrotizing layer inside impede medications to reach the inflammation and destruction zone when applied as intranasal as directly into the cavity. Techniques for drug delivery to the perifocal zone (needle-jet injections, intrapulmonary ionophoresis), dénaturation of the cavity’s pyogeneous layer (hydrodiathermocoagulation) and damming of the draining bronchi (blocking of the cavity) allow to increase a number of the destructive cavities closed 23-43.3% more and to eradicate the Mycobacteria tuberculosis 33-47.5% more copared with a complex conservative treatment.

For citations:


Smetanin A.G., Kagalovsky G.M., Shoikhet Ya.N., Semitko A.P., Konovalov V.K., Timofeyev V.V. A role of focal influence on cavity walls and near the cavity zone for increase the efficacy of treatment of destructive lung tuberculosis. PULMONOLOGIYA. 2002;(3):52-55. (In Russ.)

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)