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New abilities in treatment of bronchoobstructive syndrome in children

Abstract

The authors performed an opened randomized study of therapeutic efficacy of various medications for bronchoobstructive syndrome (BOS) treatment in different aged children. Sixty nine children aged from 1.5 months to 8 years were observed; they were divided into 2 groups equal in age, demographic and functional parameters according to medications received. Each of the groups was divided into subgroups according to BOS severity. The medications efficacy was scored for the patients’ general status, dyspnoea, cough, wheezing, the lung auscultation and for visual and mathematical characteristics of bronchophonogram which are objective parameters.

The data obtained evidence that the inhaled nebulized therapy with the modern bronchodilating drugs, such as Berotec, Salgim, ipratropium bromide, Berodual is effective in most cases (more than 97%): clinical symptoms were solved, the patients’ general status and lung function parameters became normal confirmed by normal values of bronchophonography. The nebulized therapy with ipratropium bromide (Atrovent) was reliably shown to be optimal for BOS treatment in infants in term of tolerability, efficiency and safety.

About the Authors

A. B. Malakhov
Ивановская государственная медицинская академия; детская клиническая больница скорой помощи
Russian Federation


S. A. Makarova
Ивановская государственная медицинская академия; детская клиническая больница скорой помощи
Russian Federation


M. A. Malakhov
Ивановская государственная медицинская академия; детская клиническая больница скорой помощи
Russian Federation


V. S. Malyshev
Ивановская государственная медицинская академия; детская клиническая больница скорой помощи
Russian Federation


N. A. Sellverstova
Ивановская государственная медицинская академия; детская клиническая больница скорой помощи
Russian Federation


References

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Review

For citations:


Malakhov A.B., Makarova S.A., Malakhov M.A., Malyshev V.S., Sellverstova N.A. New abilities in treatment of bronchoobstructive syndrome in children. PULMONOLOGIYA. 2001;(4):55-59. (In Russ.)

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)