Inhaled corticosteroids (Pulmicort) for nebulized therapy of children
Abstract
This work assessed possibilities of using the inhaled nebulized corticosteroid budesonide (Pulmicort) in bronchial asthma exacerbation children. The study involved 92 children with moderate to severe bronchial asthma aged 1.5 to 14 years and one child with stenosing laryngotracheitis. Clinical data, spirography and bronchophonography results were analyzed.
Seventy eight (84.8%) children improved their condition in 1 or 2 days after inhalations of bronchodilator (berodual in doses according to the patients’ age). Insufficient bronchodilating effect was in 14 (15.2%) children. The children were divided into 2 groups: 8 of them were treated with systemic corticosteroids 2 mg/kg and 6 ones were given Pulmicort suspension via nebulizer 0.5-1 mg twice a day during 2-5 days. The children's condition became stable in both of the groups in 2 days. The children received systemic steroids improved more slowly than those given Pulmicort.
So, nebulized Pulmicort suspension demonstrates its high efficiency especially in infants and pre-school children. The nebulized therapy allows achieving the result faster than systemic steroids do. Any adverse effects of Pulmicort were noted.
About the Authors
N. A. Geppe
Московская медицинская академия им.И.М.Сеченова
Russian Federation
Russian Federation
N. A. Seliverstova
Московская медицинская академия им.И.М.Сеченова
Russian Federation
Russian Federation
A. B. Malakhov
Московская медицинская академия им.И.М.Сеченова
Russian Federation
Russian Federation
M. N. Lisitsin
Московская медицинская академия им.И.М.Сеченова
Russian Federation
Russian Federation
M. N. Snegotskaya
Московская медицинская академия им.И.М.Сеченова
Russian Federation
Russian Federation
V. S. Malyshev
Московская медицинская академия им.И.М.Сеченова
Russian Federation
Russian Federation
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Review
For citations:
Geppe N.A., Seliverstova N.A., Malakhov A.B., Lisitsin M.N., Snegotskaya M.N., Malyshev V.S. Inhaled corticosteroids (Pulmicort) for nebulized therapy of children. PULMONOLOGIYA. 2001;(2):74-79. (In Russ.)
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