Community-acquired pneumonia: consecutive therapy with levofloxacin

Abstract

The aim of the study was to Investigate efficacy and tolerability of levofloxacin given consecutively intra­venously and orally in moderate community-acquired pneumonia. The study involved 19 patients (11 females and 8 males), the average age was 43.3 yrs. The efficacy and tolerability were assessed at the 2-4-th day of the therapy and at the 3-5-th and 21-28-th days after finishing the treatment. All the patients firstly received the Intravenous levofloxacin for 3 days, then they took it orally in the dose of 500 mg daily for 6.8 day in average. According to clinical and radiological monitoring results this mode was effective in 18 patients. Adverse digestive effects were noted in 2 patients for short time and abolished after taking eubiotic and antispasmodic drugs.