An influence of sympathomimetics on heart haemodynamics in bronchial asthma patients
Abstract
We examined 74 bronchial asthma (BA) patients at different stages of the illness and under sympathomymetics therapy to assess changes in their heart haemodynamics. The patients were undergone echocardiography, doppler echography of intracardiac blood flow, lung function tests. The control group included 36 healthy persons with the appropriate age, weight, height, gender and the arterial blood pressure level. The left ventricle diastolic dysfunction was noted in the BA patients. It was more severe at the BA exacerbation and less in the stable BA and depended on the bronchial obstruction, pulmonary haemodynamics disorders, a structure and a function of the right ventricle and severity of the left ventricle concentric remodelling. Inhalation therapy of bronchial obstruction with 200 mg of Berotec (Boehringer Ingelheim) effected positively on the left ventricle diastolic filing. The changes in the left ventricle diastolic function were not strongly related to the heart beat rate.
About the Authors
L. L. Bobrov
Военно-медицинская академия
Russian Federation
Russian Federation
A. G. Obrezan
Военно-медицинская академия
Russian Federation
Russian Federation
V. P. Sereda
Военно-медицинская академия
Russian Federation
Russian Federation
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Review
For citations:
Bobrov L.L., Obrezan A.G., Sereda V.P. An influence of sympathomimetics on heart haemodynamics in bronchial asthma patients. PULMONOLOGIYA. 2003;(2):48-52. (In Russ.)
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