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Therapy of patients with severe asthma exacerbation

Abstract

The aim of this study was to evaluate an efficacy of short-acting β2-agonists used via a dosing inhaler and a spacer in therapy of severe asthma exacerbation (SAE).
Efficacy and safety of high-dose therapy with short-acting β2-agonists v'a a dosing inhaler and a spacer was analyzed in 15 SAE patients, the average age was 0.7±1.2 yrs. The efficacy of the treatment was evaluated with several clinical and functional parameters. Using a 3-ball scale a doctor assessed wheeze and cough intensities, accessory muscle use, pulsus paradoxus. Peak expiratory flow rate (PEF), heart beat rate (HBR), respiratory frequency (RF), and arterial blood pressure were also measured. A patient also assessed his dyspnoe with the 3-ball scale.
The therapy with short-acting β2-agonists via a dosing inhaler and a spacer is an effective and safe method for treatment of SAE patients.

About the Authors

N. A. Karoli
Саратовский государственный медицинский университет; Областная клиническая больница
Russian Federation


A. P. Rebrov
Саратовский государственный медицинский университет; Областная клиническая больница
Russian Federation


S. A. Chushinsky
Саратовский государственный медицинский университет; Областная клиническая больница
Russian Federation


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Review

For citations:


Karoli N.A., Rebrov A.P., Chushinsky S.A. Therapy of patients with severe asthma exacerbation. PULMONOLOGIYA. 2003;(5):63-70. (In Russ.)

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)