Surgical treatment of polypous polysinusitis in bronchial asthma patients

Abstract

We observed 302 patients with polypous polysinusitis combined with bronchial asthma and/or aspirin intolerability. They underwent endoscopic polysinusotomia. To prevent exacerbations of the pulmonary pathology and polyposis relapses all the patients were divided into 3 groups. The 1^st group (146 patients) received corticosteroids before and after the operation. The 2^nd group (133 patients) was given the same therapy before and after the operation and they were treated with topic corticosteroids in postoperative period not less than 6 months. The 3^rd group (23 patients) received 3 plasmapheresis procedures each before the operation and topic corticosteroids for long time. As a result, there were no exacerbations of the lower airway pathology at the early postoperative period and all the patients came through the operation well. The polyposis relapses in the 1^st group became quite early: for 3 yrs they have been diagnosed in 96.9% of the patients. In the 2_nd group the polyposis relapses have been become for 3 yrs in 30.1% of the patients. The 3^rd group patients have not had the polyposis relapses during this period.