Preview

PULMONOLOGIYA

Advanced search

Acoustic evaluation of the nitrogen washout time to study the process of intrapulmonary gas mixture

Abstract

A new method is proposed to study intrapulmonary gas mixture based on acoustic evaluation of nitrogen washout time while transferring the air breathing to breathing with the gas mixture of 21% O2  and 79% He. The study involving 12 healthy subjects and 14 chronic obstructive bronchitis patients made possible the quantitative assessment of the intrapulmonary gas distribution in an integral mode or separately for each the lung. The method is absolutely safe and may be used repeatedly to detect early disturbances of the intrapulmonary gas
mixture.

About the Authors

M. I. Levashov
Институт физиологии им.А.А.Богомольца НАН Украины; НИМИЦ "НОРТ" НАН Украины
Ukraine


V. A. Berezovsky
Институт физиологии им.А.А.Богомольца НАН Украины; НИМИЦ "НОРТ" НАН Украины
Ukraine


References

1. Легкие. Клиническая физиология и функциональные пробы / Комро Дж.Г., Форстер Р.Э., Дюбуа Ф.Б. и др.: Пер. с англ. М.: Медгиз; 1961.

2. Линденбратен Л .Д., Лясс Ф.М. Медицинская радиология. М.: Медицина; 1986.

3. Навратил М ., Кадлец К., Даум С. Патофизиология дыхания. М.: Медицина; 1966.

4. Немеровский Л.И. Пульмофонография. М.: Медицина; 1981.

5. Кох W.J., Mills C.J. Measurement of alveolar gas mixing in mechanically ventilated patients. Crit. Care Med. 1992; 20 (7): 924-927.

6. Kraemer R, Pacozzi S., Casaiiltci Aebischer C. Assessment of intrapulmonary disorders in children with bronchial asthma using the nitrogen elimination technique. Pneumologie 1994; 48 (9): 704-710.

7. Morris M.G. The open circuit nitrogen washout technique for measuring the lung volume in infants: methodological aspects. Thorax 1999; 54 (9): 790-795.

8. Sivan Y., Hammer Newts C.J. Measurements of high lungs volumes by nitrogen washout method. J. Appl. Physiol. 1994; 77 (3): 1562-1564.

9. Stromberg N.O., Gostavson P.M. Ventilation in homogeneity assessed by nitrogen washout and ventilation-perfusion mismatch by capnography in stable and induced airway obstruction. Pediart. Pulmonol. 2000; 29 (2): 94-102.

10. Teculescu D.B., Rebstock E., Caillier I. et al. Variability of computerized single-breath nitrogen washout test in healthy adults. Results from a field survey in French rural area. Clin. Physiol. 1993; 13 (1): 35-50.

11. Tapper R.S., Asdell S. Comparison of helium dilution and nitrogen washout measurements of functional residual capacity in infants and very young children. Pediatr. Pulmonol. 1992; 13 (4): 250-254.

12. Yuksel B., Greenough A., Chan V., Russel R.R. Comparison of helium dilution and nitrogen washout measurements of functional residual capacity in premature infants. Pediatr. Pulmonol. 1993; 16 (3): 197-200.


Review

For citations:


Levashov M.I., Berezovsky V.A. Acoustic evaluation of the nitrogen washout time to study the process of intrapulmonary gas mixture. PULMONOLOGIYA. 2003;(6):28-32. (In Russ.)

Views: 144


ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)