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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-2588</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Акустическая оценка времени замещения азота гелием при исследовании процесса внутрилегочного смешивания газов</article-title><trans-title-group xml:lang="en"><trans-title>Acoustic evaluation of the nitrogen washout time to study the process of intrapulmonary gas mixture</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левашов</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Levashov</surname><given-names>M. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Березовский</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Berezovsky</surname><given-names>V. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Институт физиологии им.А.А.Богомольца НАН Украины;&#13;
НИМИЦ "НОРТ" НАН Украины</institution><country>Ukraine</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>6</issue><fpage>28</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Левашов М.И., Березовский В.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Левашов М.И., Березовский В.А.</copyright-holder><copyright-holder xml:lang="en">Levashov M.I., Berezovsky V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/2588">https://journal.pulmonology.ru/pulm/article/view/2588</self-uri><abstract><p>Предложен способ исследования внутрилегочного смешивания газов, основанный на акустической оценке времени вымывания азота из легких при переходе с дыхания воздухом на дыхание гелиево-кислородной газовой смесью с 79% Не и 21% О2. В исследованиях на 12 практически здоровых людях и 14 больных хроническим обструктивным бронхитом показана возможность количественной оценки внутрилегочного распределения газов как в режиме интегрального, так и локального измерений для каждого легкого в отдельности. Отличительными особенностями способа является его безопасность, возможность многократного использования для выявления ранних нарушений процесса смешивания газов в легких, особенно при проведении массовых обследований.</p></abstract><trans-abstract xml:lang="en"><p>A new method is proposed to study intrapulmonary gas mixture based on acoustic evaluation of nitrogen washout time while transferring the air breathing to breathing with the gas mixture of 21% O2  and 79% He. The study involving 12 healthy subjects and 14 chronic obstructive bronchitis patients made possible the quantitative assessment of the intrapulmonary gas distribution in an integral mode or separately for each the lung. The method is absolutely safe and may be used repeatedly to detect early disturbances of the intrapulmonary gasmixture.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Легкие. Клиническая физиология и функциональные пробы / Комро Дж.Г., Форстер Р.Э., Дюбуа Ф.Б. и др.: Пер. с англ. М.: Медгиз; 1961.</mixed-citation><mixed-citation xml:lang="en">Легкие. Клиническая физиология и функциональные пробы / Комро Дж.Г., Форстер Р.Э., Дюбуа Ф.Б. и др.: Пер. с англ. М.: Медгиз; 1961.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Линденбратен Л .Д., Лясс Ф.М. Медицинская радиология. М.: Медицина; 1986.</mixed-citation><mixed-citation xml:lang="en">Линденбратен Л .Д., Лясс Ф.М. Медицинская радиология. 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