Clinical efficiency of 6-month therapy with salmeterol in COPD patients under the strong continental climate conditions of the Eastern Siberia
Abstract
The study was designed to evaluate influence of 6-month therapy with salmeterol on clinical and functional parameters and quality of life in 20 patients with moderate to severe COPD. The disease symptoms were analyzed before and in 3 and 6 months of the treatment using the Piggario scale, the lung function parameters (FEV1, FVC, TLC, RV, Raw) were measures with spirography and body plethysmography, physical tolerance was assessed in 6-minute walking test, quality of life was evaluated with the Saint George's Respiratory Questionnaire. Results showed that Salmeterol reduced dyspnoea, cough, sputum production and improved tolerance to the cold air in the COPD patients. The 6-minute walking distance and FEV1 significantly increased to the end of the study period. The quality of life improved greatly in all scales of the questionnaire. We concluded that salmeterol was reliably effective in COPD patients living at the strong continental climate of the Eastern Siberia.
About the Authors
B. A. Chernyak
Иркутский институт усовершенствования врачей
Russian Federation
Russian Federation
I. N. Trofimenko
Иркутский институт усовершенствования врачей
Russian Federation
Russian Federation
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Review
For citations:
Chernyak B.A., Trofimenko I.N. Clinical efficiency of 6-month therapy with salmeterol in COPD patients under the strong continental climate conditions of the Eastern Siberia. PULMONOLOGIYA. 2004;(3):70-76. (In Russ.)
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