Infiltrative pulmonary tuberculosis in penitentiary healthcare system

Abstract

Summary. In penitentiary healthcare facilities of Russia, infiltrative pulmonary tuberculosis (TB) with cavitation was more prevalent in patients aged 20 to 39 years. More than 90 % of them had co-morbidities. Pulmonary lesions limited by one or two lung segments were seen more often in patients with this TB form. Drug-resistant Mycobacterium tuberculosis was yielded in 56.3 % of sputum cultures and multi-drug resistant M. tuberculosis was yielded in 25 % of cases. In 15 % of MRD-TB, M. tuberculosis was resistant to the first-line and reserve antituberculosis drugs. Therefore, treatment of first-diagnosed TB patients with the chemotherapeutic I regimen (four first-line anti-TB antibiotics) could be less effective and should be started with chemotherapeutic IIB regimen (four first-line and one reserve anti-TB antibiotics).