Repeated pneumonias in children with dysplasia of the connective tissue: retrospective clinical-and-morphological trial
Abstract
An analysis of medical documents and morphological examination of resected lung samples was done in 25 children had been operated for repeated pneumonias. All the children (100 %) were diagnosed undifferentiated connective tissue dysplasia (CTD) with marked clinical features. Morphological substrate of the repeated pneumonias was various defects of the lung growth. The results showed that the CTD as a genetic systemic pathology provided repeated pneumonias in structural abnormalities of the lungs. This fact should be taken into account in the diagnostic work-up.
About the Authors
G. I. Nechaeva
Омская государственная медицинская академия; ДГКБ № 3
Russian Federation
Competing Interests:
Russian Federation
Competing Interests:
No
M. V. Vershinina
Омская государственная медицинская академия; ДГКБ № 3
Russian Federation
Competing Interests:
Russian Federation
Competing Interests:
No
I. A. Viktorova
Омская государственная медицинская академия; ДГКБ № 3
Russian Federation
Competing Interests:
Russian Federation
Competing Interests:
No
S. I. Viktorov
Омская государственная медицинская академия; ДГКБ № 3
Russian Federation
Competing Interests:
Russian Federation
Competing Interests:
No
I. V. Druk
Омская государственная медицинская академия; ДГКБ № 3
Russian Federation
Competing Interests:
Russian Federation
Competing Interests:
No
References
1. Оганезова Г.С. Особенности течения инфекционных воспалительных заболеваний легких у детей и подростков на фоне пороков развития органов дыхания: Дис. ... канд. мед. наук. М.; 1998.
2. Черняев A.JJ. Хроническая пневмония с позиций патологоанатома. Рос. мед. журн. 2000; 4: 34-36.
3. Кадурина Т.Н. Наследственные коллагенопатии (клиника, диагностика, лечение и диспансеризация). СПб.: Невский диалект; 2000.
4. Grahame R. Heritable disorders of connective tissue. Best Pract. Res. Clin. Rheumatol. 2000; 14: 345-361.
5. Яковлев В.М., Нечаева Г.И. Кардио-респираторные синдромы при дисплазии соединительной ткани (патогенез, клиника, диагностика и лечение). Омск: ОГМА; 1994. 217.
Review
For citations:
Nechaeva G.I., Vershinina M.V., Viktorova I.A., Viktorov S.I., Druk I.V. Repeated pneumonias in children with dysplasia of the connective tissue: retrospective clinical-and-morphological trial. PULMONOLOGIYA. 2004;(5):61-66. (In Russ.)
Views:
443
Email this article 