Investigation of total lipid peroxidation level, antioxidative activity level and antioxidant enzyme activity in malignant and benign lung neoplasm samples
Abstract
Total lipid peroxidation level (TLP), antioxidative activity level (AOA) and antioxidant enzyme activity (super-oxyde dismutase, catalase) were studied in malignant and benign lung neoplasm samples. We examined 65 patients with malignant tumors and 30 ones with benign tumors. The antioxidant enzyme activity was reduced, the TLP level was increased and the AOA was inhibited in malignant tumors. Intensity of these disorders depended on histological type of the tumor and grade of malignancy: they were most severe in adenocarcinoma and mildest in bronchioloalveolar carcinoma.
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For citations:
Matskevich G.N. Investigation of total lipid peroxidation level, antioxidative activity level and antioxidant enzyme activity in malignant and benign lung neoplasm samples. PULMONOLOGIYA. 2004;(6):40-43. (In Russ.)
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