Factors influencing on quality of life in asthma patients
Abstract
The aim of this study was to evaluate a role of different demographic factors and asthma symptoms on quality of life In asthmatic patients. This wide-spread population-based study included 2100 adults aged 18 to 74 years from 22 regions of Russia (1050 patients with well-controlled asthma and 1050 patients with poorcontrolled asthma).
Influence of demographic factors (age and gender of a patient, occupation, education level, employment, family status, number of family members, personal Income, smoking history) and features of asthma course (duration and severity of the disease, need in bronchodilators, nighttime asthma symptoms, asthma control, current therapy) was estimated. A Russian analogue of general questionnaire MOS — SF36 and a Russian version of the specific Asthma Quality of Life Questionnaire (AQLQ) were used in this study.
The independent factors influencing on the quality of life in asthma patients were established. The most Important factors were the disease control and nighttime asthma symptoms. Current therapy of asthma Influenced on the quality of life controversially. Combined therapy with Inhaled corticosteroids and long-acting p-agonists provided the most improvement In the quality of life.
About the Authors
A. G. Chuchalin
НИИ пульмонологии Минздрава РФ; Лига содействия клиническим исследованиям и защите прав участников фармацевтического рынка
Russian Federation
Russian Federation
A. S. Belevsky
НИИ пульмонологии Минздрава РФ; Лига содействия клиническим исследованиям и защите прав участников фармацевтического рынка
Russian Federation
Russian Federation
I. V. Smolenov
НИИ пульмонологии Минздрава РФ; Лига содействия клиническим исследованиям и защите прав участников фармацевтического рынка
Russian Federation
Russian Federation
N. A. Smirnov
НИИ пульмонологии Минздрава РФ; Лига содействия клиническим исследованиям и защите прав участников фармацевтического рынка
Russian Federation
Russian Federation
Ya. G. Alexeeva
НИИ пульмонологии Минздрава РФ; Лига содействия клиническим исследованиям и защите прав участников фармацевтического рынка
Russian Federation
Russian Federation
References
1. What is quality of life? — 2000; 1 (9): 1-6.
2. Wiklund /., Dimenas E., Wahl M. Factors of importance when evaluating quality of life in clinical trials. Control. Clin. Trials 1990; 11: 169-179.
3. The WHOQOL group. Wld Hlth Forum 1996; 17: 354-356.
4. Бронхиальная астма: руководство для врачей России. Формулярная система. Прил. к журн. "Пульмонология"/Чучалин А.Г., Медников Б.Л., Белевский А.С. и др. М.; 1999.
5. Guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. National Asthma Education Program. Expert panel report. 2002.
6. Juniper E.F. Quality-of-life considerations in the treatment of asthma. PharmacoEconomics 1995; 8 (2): 123-138.
7. Bateman E.D., Bousquet J., Braunstein C.L. Is overall asthma control being achieved? A hypothesis-generating study. Eur. Respir. J. 2001; 17 (4): 589-595.
8. Ware J.E. SF-36 Health Survey. Manual and interpretation guide. Second printing. Boston, Massachusetts: The Health Institute. New England Medical Center; 1997.
9. Juniper E.F., Guyatt G.H., Ferrie P.J., Griffith L.E. Measuring quality of life in asthma. Am. Rev. Respir. Dis. 1993; 147: 832-838.
Review
For citations:
Chuchalin A.G., Belevsky A.S., Smolenov I.V., Smirnov N.A., Alexeeva Ya.G. Factors influencing on quality of life in asthma patients. PULMONOLOGIYA. 2004;(1):67-83. (In Russ.)
Views:
247
Email this article 