Challenges in the differential diagnosis of primary diffuse large B-cell non-Hodgkin’s lymphoma of the lung
N. V. Chernichenko,
I. Dzh. Lagkueva,
Ya. Yu. Murzin, 
P. M. Kotlyarov,
O. P. Bliznyukov,
V. A. Solodkiy
P. M. Kotlyarov,
O. P. Bliznyukov,
V. A. Solodkiy https://doi.org/10.18093/0869-0189-2021-31-3-384-390
Abstract
The described clinical case shows the challenges in the differential diagnosis of primary diffuse large B-cell lymphoma of the lung. It has been shown that the diagnosis can be made only by a morphological examination of a biopsy specimen, and the specimen should be representative and allow for full histological and immunohistochemical testing. A correct diagnostic algorithm, an interdisciplinary approach, the use of new technologies, particularly radiation imaging methods, to reliably determine the primary localization and spread of the pathological process, biopsies for the morphological confirmation shorten the time to diagnosis. A quick diagnosis improves the treatment outcomes and affects the quality of life and life expectancy of patients.
About the Authors
N. V. Chernichenko
Federal Russian Scientific Radiology Center, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Natal’ya V. Chernichenko, Doctor of Medicine, Leading Researcher, Research Department of Surgery and Surgical Technologies in Oncology
ul. Profsoyuznaya 86, Moscow, 117997
tel.: (495) 334-81-86
I. Dzh. Lagkueva
Federal Russian Scientific Radiology Center, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Irina Dzh. Lagkueva, Candidate of Medicine, Researcher, Research Department of Novel Technologies and Radiological Diagnosis of Diseases
ul. Profsoyuznaya 86, Moscow, 117997
tel.: (495) 334-81-86
Ya. Yu. Murzin
Federal Russian Scientific Radiology Center, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Yaroslav Yu. Murzin, Candidate of Medicine, Oncologist, Thoracic Surgeon, the 2nd Department оf Surgery for Tumors оf the Skin, Soft Tissues, Neck
ul. Profsoyuznaya 86, Moscow, 117997
tel.: (495) 334-81-86
P. M. Kotlyarov
Federal Russian Scientific Radiology Center, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Petr M. Kotlyarov, Doctor of Medicine, Professor, Head of Research Department of Novel Technologies and Radiological Diagnosis of Diseases. Affiliation ID: 60105123
ul. Profsoyuznaya 86, Moscow, 117997
tel.: (495) 334-81-86
O. P. Bliznyukov
Federal Russian Scientific Radiology Center, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Oleg P. Bliznyukov, Doctor of Medicine, Head of Pathological Department
ul. Profsoyuznaya 86, Moscow, 117997
tel.: (495) 334-81-86
V. A. Solodkiy
Federal Russian Scientific Radiology Center, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Vladimir A. Solodkiy, Doctor of Medicine, Professor, Academician of Russian Academy of Sciences, Director
ul. Profsoyuznaya 86, Moscow, 117997
tel.: (495) 334-81-86
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Review
For citations:
Chernichenko N.V., Lagkueva I.D., Murzin Ya.Yu., Kotlyarov P.M., Bliznyukov O.P., Solodkiy V.A. Challenges in the differential diagnosis of primary diffuse large B-cell non-Hodgkin’s lymphoma of the lung. PULMONOLOGIYA. 2021;31(3):384-390. (In Russ.) https://doi.org/10.18093/0869-0189-2021-31-3-384-390
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