Antibacterial therapy in patients with bronchial asthma and latent Mycoplasma pneumoniae infection
https://doi.org/10.18093/0869-0189-2007-0-1-64-68
Abstract
Influence of Mycoplasma pneumoniae (Мр) infection on asthma course and quality of life (QoL) of asthmatic patients was studied. Mp infection was diagnosed using specific immunoglobulins and PCR. The 6-week course of antibacterial therapy with azithromycin (Zitrolidum) was administered followed by analysis of clinical features and QoL. The latter was done using the AQLQ questionnaire with consideration of gender, asthma severity, contamination with and Мp eradication. Negative influence of Мp on clinical course of asthma and QoL was found. Therapy with Zitrolidum led to Мp eradication in 43 % of the cases, clinical improvement and increasing QoL in successfully treated patients. The results allow recommendation of azithromycin as a possible addition to the basic therapy of patients with severe asthma and laboratory signs of Mp infection.
About the Authors
R. F. Khamitov
Казанский государственный медицинский университет МЗ РФ
Russian Federation
Russian Federation
L. Yu. Palmova
Казанский государственный медицинский университет МЗ РФ
Russian Federation
Russian Federation
V. G. Novozhenov
Государственный институт усовершенствования врачей МО РФ
Russian Federation
Russian Federation
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Review
For citations:
Khamitov R.F., Palmova L.Yu., Novozhenov V.G. Antibacterial therapy in patients with bronchial asthma and latent Mycoplasma pneumoniae infection. PULMONOLOGIYA. 2007;(1):64-68. (In Russ.) https://doi.org/10.18093/0869-0189-2007-0-1-64-68
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