Vascular reactivity in patients with bronchial asthma
https://doi.org/10.18093/0869-0189-2008-0-6-63-66
Abstract
Ultrasound investigation was done in 96 patients with bronchial asthma to define changes in endothelium-dependent and endothelium-independent reactivity of brachial artery and their relations to central and pulmonary hemodynamics as well as to the airway reactivity. Tests with reactive hyperemia and nitroglycerine revealed disorders of vascular reactivity (decrease in endothelium-dependent and endothelium-independent brachial artery dilation) which progressively worsened while severity of the disease increased. Dilation disorders in the systemic circulation closely related to the left ventricle diastolic dysfunction, increased total pulmonary vascular resistance and the airway reactivity.
About the Authors
T. V. Smirnova
ГУ "Дальневосточный научный центр физиологии и патологии дыхания СО РАМН"
Russian Federation
Russian Federation
Yu. M. Perelman
ГУ "Дальневосточный научный центр физиологии и патологии дыхания СО РАМН"
Russian Federation
Russian Federation
V. P. Kolosov
ГУ "Дальневосточный научный центр физиологии и патологии дыхания СО РАМН"
Russian Federation
Russian Federation
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Review
For citations:
Smirnova T.V., Perelman Yu.M., Kolosov V.P. Vascular reactivity in patients with bronchial asthma. PULMONOLOGIYA. 2008;(6):63-66. (In Russ.) https://doi.org/10.18093/0869-0189-2008-0-6-63-66
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