INCREASED SUSCEPTIBILITY TO MYCOBACTERIUM TUBERCULOSIS IN PATIENTS WITH X-LINKED CHRONIC GRANULOMATOUS DISEASE
https://doi.org/10.18093/0869-0189-2011-0-1-50-54
Abstract
Summary. The article has presented comprehensive data on pathogenesis and clinical features of complications of BCG vaccination and of tuberculosis course in 9 patients with confirmed X-linked chronic granulomatous disease. We observed a high incidence of complications of BCG vaccination in thiscohort. After vaccination, all the patients developed regional lymphadenitis and a high risk of occurrence of pulmonary tuberculosis in case of M. tuberculosis infection. To prevent complication of BCG vaccination, genealogical analyze of the patient's mother is necessary (early childrhood mortality, family cases of tuberculosis or / and BCG complications, etc.)
About the Authors
S. O. Sharapova
Республиканский научно6практический центр детской онкологии и гематологии
Russian Federation
Russian Federation
аспирант научного отдела лаборатории иммунологии
223040, Беларусь, Минский район, п/о Лесное62.
Тел.: (+375-017) 265-40-68.
A. S. Pozdnyakova
ГУО "Белорусская медицинская академия последипломного образования"
Russian Federation
Russian Federation
к. м. н., доцент кафедры фтизиопульмонологии ,главный внештатный фтизиопедиатр Министерства Здравоохранения Республики Беларусь
220013, Беларусь, Минск, ул. П. Бровки, 3, к. 3.
Тел.: (+375-017) 265-25-31.
S. N. Aleshkevich
Республиканский научно6практический центр детской онкологии и гематологии
Russian Federation
Russian Federation
врач-гематолог консультационно-поликлинического отделения
223040, Беларусь, Минский район, п/о Лесное62.
Тел.: (+375-017) 265-40-85.
A. A. Migas
Республиканский научно6практический центр детской онкологии и гематологии
Russian Federation
Russian Federation
мл. науч. сотрудник лаборатории молекулярной биологии научного отдела
223040, Беларусь, Минский район, п/о Лесное62.
Тел.: (+375-017)265-40-68.
M. V. Belevtsev
Республиканский научно6практический центр детской онкологии и гематологии
Russian Federation
Russian Federation
к. б. н., зав. лабораторией иммунологии научного отдела
223040, Беларусь, Минский район, п/о Лесное62.
Тел.: (+375-017) 265-40-89.
References
1. Notarangelo L.D. Primary immunodeficiencies. J. Allergy Clin. Immunol. 2010; 125 (2): 182–194.
2. Notarangelo L.D., Fischer A., Geha R.S. et al. Primary immunodeficiencies: 2009 update. J. Allergy Clin.Immunol. 2009; 124: 1161–1178.
3. Reichenbach J., Rosenzweig S., Doffinger R. et al. Mycobacterial diseases in primary Immunodeficiencies. Curr.Opin. Allergy Clin. Immunol. 2001; 1: 503–511.
4. Cooper A.M. Cell mediated immune responses in tuberculosis. Ann. Rev. Immunol. 2009; 27: 393-422.
5. North R.J., Jung Yu.-J. Immunity to tuberculosis. Ann. Rev.Immunol. 2004; 22: 599–623.
6. Al-Muhsen S., Casanova J.-L. The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases. J. Allergy Clin. Immunol. 2008; 122 (6): 1043–1051.
7. Ochs H.D., Smith C.I.E., Puck J.M. Primary immunodeficiency diseases, a molecular and genetic approach, second edition. New York: Oxford University Press; 2007.
8. van den Berg J.M., van Koppen E., Ahlin A. et al. Chronic granulomatous disease: The European experience. PLoS One 2009; 4 (4): 1–10.
9. Rodrigues L.C., Divan V.K., Wheeler J.G. Protective effect of BCG against tuberculous meningitis and miliary tuberculosis: A meta analysis. Int. J. Epidemiol. 1993; 22 (6):1154–1158.
10. Леви Д.Т., Аксенова В.А., Закирова Н.Р. и др. Вакцинация БЦЖ: характеристика препаратов и причины поствакцинальных осложнений. Пробл. туб. 1999; 4: 4–7.
11. Sadeghi-Shanbestari M., Ansarin K., Maljaei S.H. et al.Immunologic aspects of patients with disseminated bacilli Calmette-Guerin disease in north west of Iran. Ital. J.Pediatr. 2009; 35 (42): 1–5.
12. Elloumi H.Z., Holland S.M. Diagnostic assays for chronic granulomatous disease and other neutrophil disorders.Meth. Mol. Biol.: Neutrophil Meth. Protocols. 2007; 412:505–523.
13. Hesseling A.C., Rabie H., Marais B.J. et al. Bacille Calmette-Guerin vaccine-induced disease in HIV-infected and HIV-uninfected children. Clin. Infect. Dis. 2006; 42(4): 548–558.
14. Bustamante J., Aksu G., Vogt G. et al. BCG-osis and tuberculosis in a child with chronic granulomatous disease.J. Allergy Clin. Immunol. 2007; 120 (1): 32–38.
15. Jou R., Huang W.L., Su W.J. Tokyo 172 BCG vaccination complications, Taiwan. Emerg. Infect. Dis. 2009; 15 (9):1525–1526.
16. McShane H. Vaccine strategies against tuberculosis. Swiss.Med. Wkly 2009; 139 (11–12): 156–160.
17. Swaminathan S., Rekha B. Pediatric tuberculosis: global overview and challenges. Clin. Infect. Dis. 2010; 15 (50,suppl. 3): 184–194.
Review
For citations:
Sharapova S.O., Pozdnyakova A.S., Aleshkevich S.N., Migas A.A., Belevtsev M.V. INCREASED SUSCEPTIBILITY TO MYCOBACTERIUM TUBERCULOSIS IN PATIENTS WITH X-LINKED CHRONIC GRANULOMATOUS DISEASE. PULMONOLOGIYA. 2011;(1):50-54. (In Russ.) https://doi.org/10.18093/0869-0189-2011-0-1-50-54
Views:
808
Email this article 