Полиморфизм гена ADRB2: роль в предрасположенности к заболеванию, тяжести течения и терапевтическом ответе при хронической обструктивной болезни легких
Аннотация
Полиморфизм гена ADRB2: роль в предрасположенности к заболеванию, тяжести течения и терапевтическом ответе при хронической обструктивной болезни легких.
Об авторах
О. А. Цветкова
ГБОУ ВПО "Первый Московский государственный медицинский университет им. И.М.Сеченова" Минздрава России
Россия
Россия
д. м. н., проф. кафедры госпитальной терапии № 1 лечебного факультета
119991, Москва, ул. Трубецкая, 8, стр. 2. Тел.: 8 (916) 570-38-80.
М. Х. Мустафина
ГБОУ ВПО "Первый Московский государственный медицинский университет им. И.М.Сеченова" Минздрава России
Россия
Россия
аспирант кафедры госпитальной терапии № 1 лечебного факультета
119991, Москва, ул. Трубецкая, 8, стр. 2. Тел.: 8 (916) 478-59-42.
Список литературы
1. Nowak D., Berger K., Lippert B. et al. Epidemiology and health economics of COPD across Europe. Treat. Respir. Med. 2005; 4: 381–395.
2. Davis R.M., Novotny T.E. The epidemiology of cigarette smoking and its impact on chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 1989; 140: 82–84.
3. Joos L., Weir T.D., Connett J.E. et al. Polymorphisms in the β2-adrenergic receptor and bronchodilator response, bronchial hyperresponsiveness, and rate of decline in lung function in smokers. Thorax 2003; 58: 703–707.
4. Sampsonas F., Karkoulias K., Kaparianos A., Spiropoulos K. Genetics of chronic obstructive pulmonary disease, beyond alpha1-antitrypsin deficiency. Curr. Med. Chem. 2006; 13: 2857–2873.
5. Joos L., Pare′ P.D., Sandford A.J. Genetic risk factors for chronic obstructive pulmonary disease. Swiss. Med. Wkly 2002; 132: 27–37.
6. Silverman E.K., Chapman H.A., Drazen J.M. et al. Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis. Am. J. Respir. Crit. Care Med. 1998; 57: 1770–1778.
7. Tierney L.M., McPhee S.J., Papadakis M.A. et al. Current medical diagnosis and treatment. Stamford, CT: Appleton and Lange; 1997. 241–260
8. Barnes P.J., Lee T.H. Recent advances in asthma. Postgrad. Med. J. 1992; 68: 942–953.
9. Kobilka B.K., Dixon R.A., Frielle H.G. et al. cDNA for the human β2-adrenoreceptor; a protein with multiple membrane spanning domains and encoded by a gene whose chromosomal location is shared by the receptor for plateletderived growth factor. Proc. Natl. Acad. Sci. USA 1987; 84: 46–50.
10. Reihsaus E., Innis M., MacIntyre N. et al. Mutations in the gene coding for the β2-adrenergic receptor in normal and asthmatic subjects. Am. J. Respir. Cell. Mol. Biol. 1993; 8: 334–339.
11. Liggett S.B. Polymorphisms of the β2-adrenergic receptor and asthma. Am. J. Respir. Crit. Care Med. 1997; 156: 5156–5162.
12. Hall I.P. β2-adrenoceptor polymorphisms: are they clinically important? Thorax 1996; 51: 351–353.
13. Turki J., Pak J., Green S.A. et al. Genetic polymorphisms of the β2-adrenergic receptor in nocturnal and nonnocturnal asthma: evidence that Gly16 correlates with the nocturnal phenotype. J. Clin. Invest. 1995; 95: 1635–1641.
14. Green S.A., Turki J., Innis M. et al. Amino-terminal polymorphisms of the human β2-adrenergic receptor impart distinct agonist-promoted regulatory properties. Biochemistry 1994; 33: 9414–9419.
15. Hall I.P., Wheatley A., Wilding P. et al. Association of the Glu27 β2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects. Lancet 1995; 345: 1213–1214.
16. Dewar J.C., Wilkinson J., Wheatley A. et al. The glutamine 27 beta2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families. J. Allergy Clin. Immunol. 1997; 100: 261–265.
17. Hizawa N., Makita H., Nasuhara Y. et al. Beta2-adrenergic receptor genetic polymorphisms and short-term bronchodilator responses in patients with COPD. Chest 2007; 132: 1485–1492.
18. Hersh C.P. Pharmacogenetics of chronic obstructive pulmonary disease: challenges and opportunities. Pharmacogenomics 2010; 11 (2): 237–247.
19. Vacca G., Schwabe K. Polymorphisms of the β2-adrenoreceptor gene in chronic obstructive pulmonary disease. Ther. Adv. Respir. Dis. 2009; 3: 3.
20. Ho L.+I., Harn H.+J., Chen C.+H., Tsai N.+M. Polymorphism of the β2-adrenoceptor in COPD in Chinese subjects. Chest 2001; 120: 1493–1499.
21. Kim W.J., Oh Y.M., Sung J. et al. Lung function response to 12-week treatment with combined inhalation of long-acting β2-agonist and glucocorticoid according to ADRB2 polymorphism in patients with chronic obstructive pulmonary disease. Lung 2008; 186 (6): 381–386.
22. Umeda N., Yoshikawa T., Kanazawa H. et al. Association of β2-adrenoreceptor genotypes with bronchodilatory effect of tiotropium in COPD. Respirology 2008; 13 (3): 346–352.
23. Mokry M., Joppa P., Slaba E. et al. β2-adrenergic receptor haplotype and bronchodilator response to salbutamol in patients with acute exacerbations of COPD. Med. Sci. Monit. 2008; 14 (8): CR392–CR398.
24. Niu Li+ming, Liang Ying. Effect of polymorphisms in the β2-adrenergic receptor on the susceptibility and pulmonary function of patients with chronic obstructive pulmonary disease: a meta-analysis. Chin. Med. J. 2012; 125 (12): 2213–2218.
25. Thomsen M., Nordestgaard B.G. β2-adrenergic receptor polymorphisms, asthma and COPD: two large populationbased studies. Eur. Respir. J. 2012; 39: 558–566.
26. Kim W.J., Hersh C.P., DeMeo D.L. et al. Genetic association analysis of COPD candidate genes with bronchodilator responsiveness. Respir. Med. 2009; 103 (4): 552–557.
27. Lima J.J., Blake K.V., Tantisira K.G., Weiss S.T. Pharmacogenetics of asthma. Curr. Opin. Pulm. Med. 2009; 15 (1): 57–62.
28. Hawkins G.A., Weiss S.T., Bleecker E.R. Clinical consequences of ADRB2 polymorphisms. Pharmacogenomics 2008; 9 (3): 349–358.
29. Bleecker E.R., Meyers D.A. ADRB2 polymorphism and budesonide / formoterol response in chronic obstructive pulmonary disease. Chest. Prepublished online March 1, 2012.
Для цитирования:
Цветкова О.А., Мустафина М.Х. Полиморфизм гена ADRB2: роль в предрасположенности к заболеванию, тяжести течения и терапевтическом ответе при хронической обструктивной болезни легких. Пульмонология. 2013;(2):5-9. https://doi.org/10.18093/0869-0189-2013-0-2-5-9
For citation:
Tsevtkova O.A., Mustafina M.K. ADRB2 gene polymorphism: a role for predisposition, course and therapeutic response in chronic obstructive pulmonary disease. Russian Pulmonology. 2013;(2):5-9. (In Russ.) https://doi.org/10.18093/0869-0189-2013-0-2-5-9
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