Inhalation antibacterial drugs: current opportunities for use in respiratory infections
https://doi.org/10.18093/0869-0189-2020-30-3-320-328
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Abstract
The need to find ways to improve the effectiveness of antibacterial therapy is due to the dramatic escalation of resistance to antibacterial drugs (ABD), with the growth rate of resistance of ABD microorganisms ahead of the new drugs development. According to available data, the pathway of ABD administration may correlate with the phenomenon of resistance development to ABD. Actual data on existing inhalation ABDs, allowing to estimate their efficiency and safety, are considered in the article. In the treatment of patients with infectious respiratory diseases, an alternative to the systemic use of ABD may be inhalation administration of a number of ABDs, whose activity depends on concentration.
About the Authors
S. K. Zyryanov
The Peoples' Friendship University of Russia (Institute of Medicine); Moscow State City Clinical Hospital No.24, Moscow City Department of Health Care
Russian Federation
Competing Interests: not
Russian Federation
Sergey K. Zyryanov - Doctor of Medicine, Professor, Head of Department of General and Clinical Pharmacology, PFUR, Deputy Chief Physician, MSCCHNo.24, Moscow City Department of Health Care.
Ul. Miklukho-Maklaya 6, Moscow, 117198; Ul. Pistsovaya 10, Moscow, 127015, tel.: (495) 787-38-03
Competing Interests: not
O. I. Butranova
The Peoples' Friendship University of Russia (Institute of Medicine)
Russian Federation
Competing Interests: not
Russian Federation
Olga I. Butranova - Candidate of Medicine, Assistant Professor, Chair of General and Clinical Pharmacology.
Ul. Miklukho-Maklaya 6, Moscow, 117198; tel.: (903) 376-71-40Competing Interests: not
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Zyryanov S.K., Butranova O.I. Inhalation antibacterial drugs: current opportunities for use in respiratory infections. PULMONOLOGIYA. 2020;30(3):320-328. (In Russ.) https://doi.org/10.18093/0869-0189-2020-30-3-320-328
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