Osteoporosis in cystic fibrosis patients: prevention and therapeutic opportunities
https://doi.org/10.18093/0869-0189-2017-27-4-537-545
Abstract
As the life expectancy of patients with cystic fibrosis (CF) increases, the rate of pulmonary and extrapulmonary complications grows and greater contributes to worsening of general somatic status of the patients. One of such complications is osteoporosis. Osteoporosis is a systemic disease that is characterized by decreased bone density and increased risk of fractures in minimal trauma. The role of osteoporosis in CF patients is defined by consequences of osteoporotic fractures which are immobilization, failure of bronchial tree drainage, exacerbation of respiratory infection, and progress of respiratory failure. Therefore, prevention and treatment of osteoporosis is an important issue of adult CF patients.
About the Authors
I. A. Baranova
N.I.Pirogov Russian State National Research Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Doctor of Medicine, Professor at Department of Hospital Therapy, Pediatric Faculty,
ul. Ostrovityanova 1, Moscow, 117997
E. I. Kondrat'eva
Federal Medical Genetic Academic Center, Russian Academy of Science;
Moscow Regional Referral and Diagnostic Center for Children
Russian Federation
Russian Federation
Doctor of Medicine, Professor, Head of Research and Clinical Division of Cystic Fibrosis, ul. Moskvorech'e 1, Moscow, 1115478;
Head of Department of Cystic Fibrosis, ul. Kominterna 24A, build, 1, Mytishchi of Moscow oblast’, 141011
S. A. Krasovskiy
Federal Medical Genetic Academic Center, Russian Academy of Science;
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia;
D.D.Pletnev City Clinical Hospital, Moscow Healthcare Department
Russian Federation
Russian Federation
Senior Researcher at Research and Clinical Division of Cystic Fibrosis, ul. Moskvorech'e 1, Moscow, 1115478;
Candidate of Medicine, Senior Researcher at Laboratory of Cystic Fibrosis, ul. Odinnadtsataya Parkovaya 32, build. 4, Moscow, 105077;
pneumologist at the 2nd Pulmonology Department, ul. Odinnadtsataya Parkovaya 32, Moscow, 105077
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Review
For citations:
Baranova I.A., Kondrat'eva E.I., Krasovskiy S.A. Osteoporosis in cystic fibrosis patients: prevention and therapeutic opportunities. PULMONOLOGIYA. 2017;27(4):537-545. (In Russ.) https://doi.org/10.18093/0869-0189-2017-27-4-537-545
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