Endothelial damage in patients with asthma and co-morbid coronary heart disease
https://doi.org/10.18093/0869-0189-2017-27-4-490-495
Abstract
Recently, growing number of patients with bronchial asthma (BA) and co-morbid cardiovascular diseases has been noted. The purpose of this study was to investigate a relationship between markers of endothelial dysfunction and parameters of arterial stiffness in patients with BA and stable class 1 to 3 angina pectoris. Methods. We examined 32 BA patients 32 patients with co-morbidity of BA and ischemic heart disease (IHD). Results. Arterial stiffness was increased in BA patients. Co-morbidity of BA and IHD resulted in more prominent increase in the arterial stiffness and endothelial dysfunction. Conclusion. Diagnosis IHD in BA patients is quite difficult in clinical practice. Markers of this co-morbidity are needed to improve the diagnostic work-up.
About the Authors
Y. I. Verigo
V.F.Voyno-Yasenetskiy Krasnoyarsk State Medical University, Healthcare Ministry of Russia;
Krasnoyarsk Territorial State Teaching Hospital
Russian Federation
Russian Federation
Postgraduate student, Department No.2 of Internal Medicine and Postgraduate Physician Training Course,
ul. Partizana Zheleznyaka 1, Krasnoyarsk, 660022
I. V. Demko
V.F.Voyno-Yasenetskiy Krasnoyarsk State Medical University, Healthcare Ministry of Russia;
Krasnoyarsk Territorial State Teaching Hospital
Russian Federation
Competing Interests:
Russian Federation
Doctor of Medicine, Professor, Head of Department No.2 of Internal Medicine and Postgraduate Physician Training Course, ul. Partizana Zheleznyaka 1, Krasnoyarsk, 660022;
Head of Center of Pulmonology and Allergology, ul. Partizana Zheleznyaka 3, Krasnoyarsk, 660022
Competing Interests:
д. м. н., профессор, заведующая кафедрой внутренних болезней № 2 с курсом постдипломного образования, Красноярск, ул. Партизана Железняка, 1;
заведующая легочно-аллергологическим центром, 660022, Красноярск, ул. Партизана Железняка, 3
M. M. Petrova
V.F.Voyno-Yasenetskiy Krasnoyarsk State Medical University, Healthcare Ministry of Russia
Russian Federation
Russian Federation
Doctor of Medicine, Professor, Head of Department of Outpatient Therapy, Family Medicine and Healthy Lifestyle with Postgraduate Physician Training Course,
ul. Partizana Zheleznyaka 1, Krasnoyarsk, 660022
E. A. Sobko
V.F.Voyno-Yasenetskiy Krasnoyarsk State Medical University, Healthcare Ministry of Russia;
Krasnoyarsk Territorial State Teaching Hospital
Russian Federation
Russian Federation
Doctor of Medicine, Associate Professor at Department No.2 of Internal Medicine and Postgraduate Physician Training Course, ul. Partizana Zheleznyaka 1, Krasnoyarsk, 660022;
Head of Division of Pulmonology and Allergology, Center of Pulmonology and Allergology, ul. Partizana Zheleznyaka 3, Krasnoyarsk, 660022
A. E. Ryazanov
Krasnoyarsk Territorial State Teaching Hospital
Russian Federation
Russian Federation
a cardiologist,
ul. Partizana Zheleznyaka 3, Krasnoyarsk, 660022
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Review
For citations:
Verigo Y.I., Demko I.V., Petrova M.M., Sobko E.A., Ryazanov A.E. Endothelial damage in patients with asthma and co-morbid coronary heart disease. PULMONOLOGIYA. 2017;27(4):490-495. (In Russ.) https://doi.org/10.18093/0869-0189-2017-27-4-490-495
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