An informative value of impulse oscillometry for diagnosis of ventilation abnormalities in patients with newly diagnosed pulmonary sarcoidosis
https://doi.org/10.18093/0869-0189-2017-27-4-439-445
Abstract
The aim of this study was to analysis the total respiratory impedance and its components and to evaluate the informative value of impulse oscillometry in comparison with conventional methods of lung function testing in patients with pulmonary sarcoidosis.
Methods. The study involved 50 patients (88% of males; mean age, 31 ± 9 years) with newly diagnosed pulmonary sarcoidosis. The diagnosis of sarcoidosis was confirmed by lung biopsy. Spirometry, body plethysmography, and impulse oscillometry were used in all patients; the lung diffusing capacity was measured.
Results. Abnormalities of the respiratory mechanics were found using the conventional diagnostic methods in 34% of the patients, including obstructive disorders in 18% and restrictive disorders in 16%; all were mild to moderate. Parameters of impulse oscillometry were abnormal only in 10% of the patients.
Conclusion. The impulse oscillometry has a low sensitivity to detect mild functional respiratory abnormalities in patients with newly diagnosed pulmonary sarcoidosis.
About the Authors
O. I. Savushkina
Acad. N.N.Burdenko The Main Military Clinical Hospital, Ministry of Defense
Russian Federation
Russian Federation
Candidate of Biology, Head of Department of Lung Function Testing, Center of Functional Diagnostic Investigations,
Moscow, Gospital'naya pl. 3, Moscow, 105229
A. V. Chernyak
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Candidate of Medicine, Head of Laboratory of Functional and Ultrasound Investigations,
ul. Odinnadtsataya Parkovaya 32, build. 4, Moscow, 105077
A. A. Zaytsev
Acad. N.N.Burdenko The Main Military Clinical Hospital, Ministry of Defense
Russian Federation
Russian Federation
Doctor of Medicine, Chief Pulmonologist,
Moscow, Gospital'naya pl. 3, Moscow, 105229
I. Ts. Kulagina
Acad. N.N.Burdenko The Main Military Clinical Hospital, Ministry of Defense
Russian Federation
Russian Federation
Candidate of Medicine, Head of Pulmonology Office,
Moscow, Gospital'naya pl. 3, Moscow, 105229
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For citations:
Savushkina O.I., Chernyak A.V., Zaytsev A.A., Kulagina I.Ts. An informative value of impulse oscillometry for diagnosis of ventilation abnormalities in patients with newly diagnosed pulmonary sarcoidosis. PULMONOLOGIYA. 2017;27(4):439-445. (In Russ.) https://doi.org/10.18093/0869-0189-2017-27-4-439-445
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