Mannose-binding lectin deficiency in respiratory diseases
https://doi.org/10.18093/0869-0189-2016-26-6-748-752
Abstract
Mannosebinding lectin is a part of the innate immunity that, being the first barrier of the antiinfectious defense, acts in first minutes or hours after pathogen challenge. The review provides data about mechanisms of action of mannosebinding lectin and its particular pathogenic role in a wide range of respiratory diseases: bacterial pneumonia, viral respiratory tract infections, tuberculosis, cystic fibrosis, chronic obstructive pulmonary disease, and asthma in adults and children.
About the Authors
S. Yu. Tereshchenko
Federal Research Institute of Medical Problems of the North, Siberian Department of Russian Academy of Medical Science
Russian Federation
Russian Federation
ul. Partizana Zheleznyaka 3G, Krasnoyarsk, 660022, Russia
Doctor of Medicine, Professor, Head of Division of Children's Somatic and Psychiatric Health, Federal Research Institute of Medical Problems of the North; tel.: (391) 2280683
E. V. Kasparov
Federal Research Institute of Medical Problems of the North, Siberian Department of Russian Academy of Medical Science
Russian Federation
Russian Federation
ul. Partizana Zheleznyaka 3G, Krasnoyarsk, 660022, Russia
Doctor of Medicine, Professor, Alternative Director of Federal Research Institute of Medical Problems of the North; tel.: (391)2280683
M. V. Smol'nikova
Federal Research Institute of Medical Problems of the North, Siberian Department of Russian Academy of Medical Science
Russian Federation
Russian Federation
ul. Partizana Zheleznyaka 3G, Krasnoyarsk, 660022, Russia
Candidate of Medicine, Leading Researcher at Laboratory of Molecular Physiology and Pathology, Federal Research Institute of Medical Problems of the North; tel.: (391) 2280683
E. V. Kuvshinova
Federal Research Institute of Medical Problems of the North, Siberian Department of Russian Academy of Medical Science
Russian Federation
Russian Federation
ul. Partizana Zheleznyaka 3G, Krasnoyarsk, 660022, Russia
Physician at Department of Pediatric Pulmonology, Federal Research Institute of Medical Problems of the North; tel.: (391) 2280683
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Review
For citations:
Tereshchenko S.Yu., Kasparov E.V., Smol'nikova M.V., Kuvshinova E.V. Mannose-binding lectin deficiency in respiratory diseases. PULMONOLOGIYA. 2016;26(6):748-752. (In Russ.) https://doi.org/10.18093/0869-0189-2016-26-6-748-752
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